Evidence map›Paper›PMID 40239364›Full record

ReviewCurrent opinion in neurobiology2025

Interoceptive processing in the nucleus of the solitary tract.

Tianxiao X Huang, Shiqi Wang, Chen Ran

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cellular coding of ingestion in the caudal brainstem.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tianxiao X HuangDepartment of Neuroscience, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
Shiqi WangDepartment of Neuroscience, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA.
Chen RanDepartment of Neuroscience, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: cran@scripps.edu.

Funding

Deconstructing brainstem circuits for visceral sensesK01DK132957 · NIDDK · SCRIPPS RESEARCH INSTITUTE, THE · PI Chen Ran · 2023 to 2026
$586k
NIDDK NIH HHS K01 DK132957
6 · The paper itself

Abstract

The interoceptive nervous system continuously monitors the status of visceral organs to synthesize internal perceptions and regulate behavioral and physiological responses. The nucleus of the solitary tract (NTS) in the brainstem serves as a central interoceptive hub and the initial site where sensory information from internal organs is processed in the brain. Here we review the neurobiological underpinnings of interoceptive processing in the NTS, focusing on recent progress enabled by modern genetic and optical tools for neural circuit dissection and neuronal recordings. Sensory information from internal organs is organized into a topographic map within the NTS, computed locally, modulated by descending inputs from higher brain regions, and distributed to downstream targets via projection neurons to control behavior and physiology. We present a sensory processing perspective on interoceptive coding within this brain structure.

Indexed as

InteroceptionSolitary NucleusAnimalsHumansNeurons

Identifiers

PMID40239364
PMCPMC13056455

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.