Evidence map›Paper›PMID 40238884›Full record

ArticleScience advances2025

Cathelicidin antimicrobial peptides mediate immune protection in marsupial neonates.

Jongbeom Park, Wenfan Ke, Aellah Kaage, Charles Y Feigin, Aaron H Griffing, Yuri Pritykin, Mohamed S Donia, Ricardo Mallarino

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jongbeom ParkDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0003-3214-858X
Wenfan KeDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-7047-5445
Aellah KaageDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0009-0004-5728-7409
Charles Y FeiginDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0003-4981-5254
Aaron H GriffingDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0001-8441-1330
Yuri PritykinLewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08540, USA.ORCID 0000-0001-6589-981X
Mohamed S DoniaDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-9604-2912
Ricardo MallarinoDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.ORCID 0000-0002-8971-4864

Funding

Using naturally evolved phenotypic variation to decipher the positional regulatory code of mammalian skinR35GM133758 · NIGMS · PRINCETON UNIVERSITY · PI Ricardo Mallarino · 2019 to 2026
$3.0M
Regulatory genomics of T cells in mouse and humanDP2AI171161 · NIAID · PRINCETON UNIVERSITY · PI Yury Pritykin · 2022 to 2026
$2.4M
Vectra Polaris Quantitative Pathology Imaging SystemS10OD030269 · OD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CROSSLAND, NICHOLAS ALEXANDER · 2021 to 2021
$402k
How to build a gliding mammal: Using natural phenotypic variation to define the molecular regulation of tissue morphogenesisF32GM139240 · NIGMS · PRINCETON UNIVERSITY · PI FEIGIN, CHARLES YAKOV · 2020 to 2022
$100k
NIAID NIH HHS DP2 AI171161NIGMS NIH HHS F32 GM139240NIGMS NIH HHS R35 GM133758NIH HHS S10 OD030269
6 · The paper itself

Abstract

Marsupial neonates are born with immature immune systems, making them vulnerable to pathogens. While neonates receive maternal protection, they can also independently combat pathogens, although the mechanisms remain unknown. Using the sugar glider (

Indexed as

Antimicrobial Cationic PeptidesAntimicrobial PeptidesCathelicidinsMarsupialiaAnimalsAnimals, NewbornMiceNeutrophilsSepsisAntimicrobial Cationic PeptidesAntimicrobial PeptidesCathelicidins

Identifiers

PMID40238884
PMCPMC12002115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.