Evidence map›Paper›PMID 40238861›Full record

ArticleJournal of primary care & community health

The Use of an Artificial Intelligence Platform OpenEvidence to Augment Clinical Decision-Making for Primary Care Physicians.

Ryan T Hurt, Christopher R Stephenson, Elizabeth A Gilman, Christopher A Aakre, Ivana T Croghan, Manpreet S Mundi, Karthik Ghosh, Jithinraj Edakkanambeth Varayil

Abstract read
In one paragraph

Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
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  6. Review
  7. Strengths and Potential Pitfalls of the Use of Artificial Intelligence in Psychiatric Education and Practice.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  8. Artificial Intelligence in Psychiatric Graduate Medical Education.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
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  15. Article
  16. Review
  17. Article
  18. Patterns of AI Use in Clinical Work by Hospitalists: Survey Study.Journal of medical Internet research · 2026
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ryan T HurtMayo Clinic, Rochester, MN, USA.
Christopher R StephensonMayo Clinic, Rochester, MN, USA.
Elizabeth A GilmanMayo Clinic, Rochester, MN, USA.ORCID 0000-0002-0166-391X
Christopher A AakreMayo Clinic, Rochester, MN, USA.
Ivana T CroghanMayo Clinic, Rochester, MN, USA.ORCID 0000-0003-3464-3525
Manpreet S MundiMayo Clinic, Rochester, MN, USA.ORCID 0000-0001-7902-3544
Karthik GhoshMayo Clinic, Rochester, MN, USA.
Jithinraj Edakkanambeth VarayilMayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) platforms can potentially enhance clinical decision-making (CDM) in primary care settings. OpenEvidence (OE), an AI tool, draws from trusted sources to generate evidence-based medicine (EBM) recommendations to address clinical questions. However, its effectiveness in real-world primary care cases remains unknown.

objectiveTo evaluate the performance of OE in providing EBM recommendations for five common chronic conditions in primary care: hypertension, hyperlipidemia, diabetes mellitus type 2, depression, and obesity.

methodsFive patient cases were retrospectively analyzed. Physicians posed specific clinical questions, and OE responses were evaluated on clarity, relevance, evidence support, impact on CDM, and overall satisfaction. Four independent physicians provided ratings using a 0 to 4 scale.

resultsOE provided accurate, evidence-based recommendations in all cases, aligning with physician plans. OE was scored on a scale of zero to four, where zero was very unclear, and four was very clear. Mean scores across cases were clarity (3.55 ± 0.60), relevance (3.75 ± 0.44), support (3.35 ± 0.49), and satisfaction (3.60 ± 0.60). However, the impact on CDM was limited (1.95 ± 1.05), as OE primarily reinforced rather than modified plans.

conclusionOE was rated high in clarity, relevance, and evidence-based support, reinforcing physician decisions in common chronic conditions. While the impact on CDM was minimal due to the study's retrospective nature, OE shows promise in augmenting the primary care physician. Prospective trials are needed to evaluate its utility in complex cases and multidisciplinary settings.

Indexed as

Artificial IntelligenceClinical Decision-MakingPhysicians, Primary CareChronic DiseaseDepressionDiabetes Mellitus, Type 2Evidence-Based MedicineFemaleHumansHyperlipidemiasHypertensionMaleMiddle AgedObesityPrimary Health CareRetrospective Studiesartificial intelligence (AI)chronic disease managementclinical decision-makingOpenEvidenceprimary care

Identifiers

PMID40238861
PMCPMC12033599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.