Evidence map›Paper›PMID 40238647›Full record

ArticleMicrobial genomics2025

Taxonomic distribution of SbmA/BacA and BacA-like antimicrobial peptide transporters suggests independent recruitment and convergent evolution in host-microbe interactions.

Nicholas T Smith, Amira Boukherissa, Kiera Antaya, Graeme W Howe, Peter Mergaert, Ricardo C Rodríguez de la Vega, Jacqui A Shykoff, Benoît Alunni, George C diCenzo

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In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. BacA(SbmA) importer of legume symbiotic NCR peptides: Protein architecture, function, and evolutionary implications.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nicholas T SmithDepartment of Biology, Queen's University, Kingston, ON, K7L 3N6, Canada.
Amira BoukherissaInstitute for Integrative Biology of the Cell, CNRS, CEA, Université Paris-Saclay, 91198, Gif-sur-Yvette, France.
Kiera AntayaDepartment of Biology, Queen's University, Kingston, ON, K7L 3N6, Canada.
Graeme W HoweDepartment of Chemistry, Queen's University, Kingston, ON, K7L 3N6, Canada.
Peter MergaertInstitute for Integrative Biology of the Cell, CNRS, CEA, Université Paris-Saclay, 91198, Gif-sur-Yvette, France.
Ricardo C Rodríguez de la VegaÉcologie Systématique et Évolution, Université Paris-Saclay, CNRS, AgroParisTech, 91198, Gif-sur-Yvette, France.
Jacqui A ShykoffÉcologie Systématique et Évolution, Université Paris-Saclay, CNRS, AgroParisTech, 91198, Gif-sur-Yvette, France.
Benoît AlunniInstitute for Integrative Biology of the Cell, CNRS, CEA, Université Paris-Saclay, 91198, Gif-sur-Yvette, France.
George C diCenzoDepartment of Biology, Queen's University, Kingston, ON, K7L 3N6, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are often produced by eukaryotes to control bacterial populations in both pathogenic and mutualistic symbioses. Several pathogens and nitrogen-fixing legume symbionts depend on transporters called SbmA (or BacA) or BclA (BacA-like) to survive exposure to AMPs. However, how broadly these transporters are distributed amongst bacteria, and their evolutionary history, is poorly understood. We used computational approaches, including phylogenetic and sequence similarity analyses, to examine the distribution of SbmA/BacA and BclA proteins across 1,255 species spanning the domain

Indexed as

Antimicrobial PeptidesBacteriaBacterial ProteinsHost Microbial InteractionsMembrane Transport ProteinsEvolution, MolecularFabaceaePhylogenySymbiosisAntimicrobial PeptidesBacterial ProteinsMembrane Transport Proteinsantimicrobial peptideshost–microbe interactionmolecular evolutionpathogenesispeptide transportrhizobium-legume symbioses

Identifiers

PMID40238647
PMCPMC12003926

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.