ReviewAngewandte Chemie (International ed. in English)2025
Bioinspired Cationic Antimicrobial Polymers.
Review in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Bacterial phospholipid selective quaternary phosphonium polymers with potent antibacterial activity.Materials today. Bio · 2026Article
- Antimicrobial Cyclic Peptidomimetics.Macromolecular rapid communications · 2026Article
- Infection responsive bio-nanoparticles as "molecular sprayer " for infection-repair integration via direct sterilization and macrophage polarization regulation.Bioactive materials · 2026Article
- Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Bactericidal Activities of Copolymers Incorporating Formylphenyl Motif for Targeting Surface Proteins.ACS polymers Au · 2025Article
- The injectable cationic double-crosslinked hydrogel facilitates bone regeneration and repair through sustained antibacterial activity.Materials today. Bio · 2025Article
- Structural Basis for Targeting the Bifunctional Enzyme ArnA.Biomolecules · 2025Article
- Poly(ethylene Glycol)-Based Peptidomimetics (Pegtides) of Antimicrobial Peptides.Chembiochem : a European journal of chemical biology · 2025Article
- Assessing the Mechanism of Action of Synthetic Nanoengineered Antimicrobial Polymers against the Bacterial Membrane ofBiomacromolecules · 2025Article
- New Generation Antibiotics Derived from DABCO-Based Cationic Polymers.Antibiotics (Basel, Switzerland) · 2025Article
- Non-Amphiphilic Antimicrobial Polymers.Angewandte Chemie (International ed. in English) · 2025Article
- Bioinspired Cationic Antimicrobial Polymers.Angewandte Chemie (International ed. in English) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of antimicrobial resistance (AMR). Without effective antibiotics, a number of medical advancements from the last century are in jeopardy, threatening our global public health and leading to a high death toll. To counteract this development, new therapeutic strategies, that are insusceptible to resistance development have to be established. Among them, antimicrobial polymers (AP)s are a promising class of materials. Their mode-of-action is highly unspecific as they kill bacteria by membrane permeabilization or precipitation of intracellular components. As such, it is unlikely for APs to be affected by AMR. This review highlights recent advances in AP design and understanding of structure-property relationships of these cationic macromolecules. One spotlight is on the polymeric architecture and how it influences AP bioactivity. A second highlight is stimuli-responsive APs and their potential to increase AP selectivity. Moreover, synergistic effects, e.g., between polymer and antibiotics are reviewed. The last focus is on in vivo applications of APs, which could pave a way toward clinical applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.