Evidence map›Paper›PMID 40238573›Full record

ArticleInternational journal of environmental research and public health2025

The Impact of Home Interventions on Dry Eye Disease (DED) Symptoms and Signs in United States Veterans.

Drew C Baeza, Johnathon Z Penso, Dhariyat M Menendez, Julio A Contreras, Sarah Rock, Anat Galor, Naresh Kumar

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Drew C BaezaBascom Palmer Eye Institute, University of Miami Health System, Miami, FL 33136, USA.
Johnathon Z PensoDepartment of Medicine, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0003-0673-6855
Dhariyat M MenendezDepartment of Health and Epidemiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Julio A ContrerasDepartment of Health and Epidemiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0001-7104-6450
Sarah RockDepartment of Health and Epidemiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.
Anat GalorBascom Palmer Eye Institute, University of Miami Health System, Miami, FL 33136, USA.ORCID 0000-0002-3026-6155
Naresh KumarDepartment of Health and Epidemiology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA.ORCID 0000-0001-6200-9172

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Differentiation of Clinical Phenotypes of Inflammatory and Neuropathic Ocular Pain Conditions with Morphologic Measures and Functional Brain ImagingU01EY034686 · NEI · BOSTON CHILDREN'S HOSPITAL · PI Eric Alan Moulton · 2022 to 2026
$4.7M
Defining bacterial members of the ocular surface microbiome and assessing stability over timeU24EY035102 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GALOR, ANAT, ST LEGER, ANTHONY J · 2023 to 2025
$3.3M
Tear protein biomarkers of refractive surgery painR33EY032468 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI AICHER, SUE A, GALOR, ANAT · 2023 to 2025
$2.9M
Dry Eye and MicroenvironmentR01EY026174 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALOR, ANAT, KUMAR, NARESH · 2016 to 2020
$1.9M
BLRD VA I01 BX004893CSRD VA I01 CX002015Department of Defense Gulf War Illness Research Program (GWIRP) W81XWH-20-1-0579Department of Defense Vision Research Program W81XWH-20-1-0820NEI NIH HHS P30 EY014801NEI NIH HHS R01 EY026174NEI NIH HHS R01EY026174NEI NIH HHS R33 EY032468NEI NIH HHS R33EY032468NEI NIH HHS U01 EY034686NEI NIH HHS U01EY034686NEI NIH HHS U24 EY035102NEI NIH HHS U24EY035102NIH Center Core Grant P30EY014801RRD VA I21 RX003883
6 · The paper itself

Abstract

backgroundThe indoor environment can contribute to dry eye disease (DED) risk, but the effects of environmental modifications on disease are still uncertain. This study evaluated the effect of home interventions that modify the indoor environment on DED symptoms and sign severity.

methodsThe prospective study consisted of two visits (6 ± 1 months apart). At each home visit, indoor environmental conditions (temperature, humidity, and airborne particulate matter) were monitored and at each clinical visit, DED symptoms and signs were examined. After the first visit, all participants received a report of their home air quality and 10 recommendations to improve their home environment. At the 6-month visit, participants indicated which interventions they implemented.

resultsA total of 99 subjects participated in the clinical evaluation and home monitoring at baseline and six-month follow-up. Their mean age was 61 years, and 26% identified as Hispanic. Most had mild or greater DED symptoms (5-Item Dry Eye Questionnaire, DEQ5 ≥ 6), with an average DEQ5 score of 10.49 ± 5.51 at baseline. In total, 77% (n = 76) implemented ≥1 intervention with home ventilation (42.4%), air conditioner filter change (36.4%), and exhaust fan use (31.3%) being the most frequent. Overall, with every intervention implemented, tear osmolarity (change from baseline to 6 months) declined by 2% (log-transformed β = 0.02; 95% confidence interval (CI) = 0.00-0.03;

conclusionsWhen provided with an objective report of home environmental conditions and remediation strategies, most participants voluntarily implemented low-cost home interventions, which reduced the severity of select DED symptoms and signs.

Indexed as

Air Pollution, IndoorDry Eye SyndromesVeteransAgedFemaleHousingHumansMaleMiddle AgedProspective StudiesUnited Statesdry eye diseaselow-cost home interventionsMeibomian gland dysfunctionosmolarityparticulate matter

Identifiers

PMID40238573
PMCPMC11941956

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.