Evidence map›Paper›PMID 40238349›Full record

ArticleAnnals of medicine2025

External validation of CLOTS-AF score in patients with atrial fibrillation undergoing transesophageal echocardiography.

Koray Kalenderoglu, Mert Ilker Hayiroglu, Lale Dinc Asarcikli, Tufan Cinar, Melih Oz, Gunseli Miray Ozdemir, Kivanc Keskin, Kadir Gurkan

Abstract readValidation Study
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Koray KalenderogluDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0002-3596-3857
Mert Ilker HayirogluDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0001-6515-7349
Lale Dinc AsarcikliDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0002-7828-9487
Tufan CinarDepartment of Medicine, University of Maryland Midtown Campus, Baltimore, MD, USA.ORCID 0000-0001-8188-5020
Melih OzDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0003-0574-5776
Gunseli Miray OzdemirDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
Kivanc KeskinDepartment of Cardiology, Yuksekova State Hospital, Hakkari, Turkey.
Kadir GurkanDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting thromboembolic events caused by left atrial appendage thrombosis (LAAT) is crucial since it is the most concerning complication of nonvalvular atrial fibrillation (NVAF).

objectiveThe objective of this study was to establish the predictive effectiveness of a novel scoring system known as the CLOTS-AF score in identifying the existence of thrombus using transesophageal echocardiography (TEE) in patients with NVAF and to compare it with the CHA

methodsThis study was conducted retrospectively with 668 NVAF patients who underwent TEE in a single centre. The patients were categorized into two categories based on the presence or absence of LAAT on TEE. The CLOTS-AF score was computed for all patients, which was then compared to the CHA

resultsThrombus was detected in the left atrial appendage (LAA) of 114 (17%) individuals. The study revealed that the thrombus (+) group had substantially higher CHA

conclusionsThis study could validate the CLOTS-AF score in an external cohort by demonstrating its significant predictive power and underscoring its vital role in clinical practice.

Indexed as

Atrial AppendageAtrial FibrillationEchocardiography, TransesophagealThromboembolismThrombosisAgedAged, 80 and overFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk AssessmentAtrial fibrillationleft atrial appendage thrombusrisk predictiontransesophageal echo

Identifiers

PMID40238349
PMCPMC12004721

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