Evidence map›Paper›PMID 40238245›Full record

ArticleFoods (Basel, Switzerland)2025

Dual-Mode Quantitative Immunochromatographic Assay for Highly Sensitive On-Site Detection of Ciprofloxacin in Fish Products.

Junqi Shen, Zhengyi Cai, Cheng Zhang, Xinyue Feng, Chenzhi Zhang, Huan Zhao, Chuanlin Yin, Bo Wang, Xiaoping Yu, Biao Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junqi ShenKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Zhengyi CaiKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Cheng ZhangKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Xinyue FengKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Chenzhi ZhangKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Huan ZhaoKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.ORCID 0009-0009-1635-9513
Chuanlin YinKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Bo WangCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, China.ORCID 0009-0005-6104-4327
Xiaoping YuKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.
Biao ZhangKey Laboratory of Microbiological Metrology, Measurement & Bio-Product Quality Security, State Administration for Market Regulation, College of Life Sciences, China Jiliang University, Hangzhou 310018, China.ORCID 0000-0001-8334-5175

Funding

the National Key Research and Development Program of China 2022YFF1101000the National Key Research and Development Programs of China 2022YFF0607905the National Key Research and Development Programs of China 2023YFF1104700the National Natural Science Foundation of China No. 32202315the National Natural Science Foundation of China No. 32402205Zhejiang Provincial Natural Science Foundation of China LQ23C200006
6 · The paper itself

Abstract

Ciprofloxacin has been extensively utilized in aquaculture due to its remarkable efficacy in preventing and treating bacterial infections in fish animals. However, the widespread application of ciprofloxacin has led to significant residue accumulation, necessitating the development of rapid, sensitive and specific detection methods. In this study, we developed a novel dual-mode quantitative immunochromatographic assay based on a portable reader and a photothermal instrument, enabling on-site ciprofloxacin detection. Under optimized conditions, the portable reader mode (Mode 1) achieved a detection range of 0.1-100.0 ng/L with a limit of detection (LOD) of 0.1 ng/mL. The photothermal instrument mode (Mode 2) achieved a detection range of 0.1-500.0 ng/mL with an LOD of 0.1 ng/mL. The sensitivity and accuracy of the method were validated using an Enzyme-Linked Immunosorbent Assay. This developed method successfully detected ciprofloxacin residues in samples of

Indexed as

aquatic product safetyciprofloxacindual-mode quantitative immunochromatographic assayphotothermal immunoassayportable readerPVP@Pd

Identifiers

PMID40238245
PMCPMC11989092

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.