Evidence map›Paper›PMID 40238190›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

A structured framework for standardized 3D leg alignment analysis: An international Delphi consensus study.

Quinten W T Veerman, Gabriëlle J M Tuijthof, Nico Verdonschot, Reinoud W Brouwer, Peter Verdonk, Annemieke van Haver, Hugo C van der Veen, Peter A J Pijpker, Judith Olde Heuvel, Roy A G Hoogeslag and 1 more

Abstract readConsensus Statement
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A structured framework for standardized 3D leg alignment analysis: An international Delphi consensus study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Quinten W T VeermanOCON Centre for Orthopaedic Surgery and Sports Medicine, Hengelo, the Netherlands.ORCID http://orcid.org/0000-0002-2774-6246
Gabriëlle J M TuijthofDepartment of Biomechanical Engineering, Faculty of Engineering Technology, University of Twente, Enschede, the Netherlands.ORCID http://orcid.org/0000-0003-4372-6584
Nico VerdonschotDepartment of Biomechanical Engineering, Faculty of Engineering Technology, University of Twente, Enschede, the Netherlands.ORCID http://orcid.org/0000-0002-7531-6523
Reinoud W BrouwerDepartment of Orthopaedic Surgery, Martini Hospital Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0002-7325-0647
Peter VerdonkDepartment of Orthopaedic Surgery, Antwerp University Hospital, Antwerp, Belgium.ORCID http://orcid.org/0000-0001-6057-8590
Annemieke van HaverMore Institute, Monica Orthopaedic Research Institute, Antwerp, Belgium.ORCID http://orcid.org/0009-0005-2901-7329
Hugo C van der VeenDepartment of Orthopaedic Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0003-1305-8968
Peter A J Pijpker3D Lab, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID http://orcid.org/0000-0001-9543-1097
Judith Olde HeuvelOCON Centre for Orthopaedic Surgery and Sports Medicine, Hengelo, the Netherlands.ORCID http://orcid.org/0000-0003-3219-8608
Roy A G HoogeslagOCON Centre for Orthopaedic Surgery and Sports Medicine, Hengelo, the Netherlands.ORCID http://orcid.org/0000-0002-1588-086X
3D Leg Alignment Consensus Expert Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo reach consensus among international experts on a structured framework for standardized 3D leg alignment analysis based on 3D bone models, ensuring consistency and improving clinical applicability.

methodsA Delphi study was performed in four rounds. Rounds 1 and 2 involved a steering and rating group that developed statements based on principles preserving the 3D complexity of anatomical structures, identified through a systematic review. These statements encompassed approaches for deriving joint centres and joint orientations, and defining coordinate systems using 3D bone models. In Rounds 3 and 4, a panel of 35 international experts, including clinicians (54%) and engineers (46%), with participants from Europe (80%), Oceania (9%), Asia (6%), and the Americas (6%), evaluated these statements. Consensus was defined as ≥80% agreement.

resultsRounds 1 and 2 resulted in 31 statements to be included in the survey. Of these, 26 achieved consensus in Round 3, with the five remaining statements refined and reaching consensus in Round 4. Experts agreed on utilising all available relevant surface data to define joint centres, joint orientations, and individual femoral and tibial coordinate systems alongside a combined leg coordinate system, and adopting central 3D axes for femoral version and tibial torsion.

conclusionsThis international Delphi consensus study provides a structured framework for a standardized 3D leg alignment analysis based on 3D bone models. This framework aims to enhance clinical applicability for preoperative planning and execution of uni- and multiplanar correction osteotomies around the knee, reduce the methodological variability in 3D leg alignment analysis literature, and improve cross-study comparability. LEVEL OF EVIDENCE: Level V.

Indexed as

FemurImaging, Three-DimensionalKnee JointTibiaDelphi TechniqueHumansModels, Anatomicalignment parametersconsensuscoordinate systemsjoint orientationknee

Identifiers

PMID40238190
PMCPMC12104791

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.