Evidence map›Paper›PMID 40238065›Full record

ArticleAnnals of surgical oncology2025

Long-Term Outcomes of Lymphedema After Immediate Lymphatic Reconstruction Following Axillary Lymph Node Dissection.

Abbas M Hassan, John P Hajj, John P Lewis, Shahnur Ahmed, Carla S Fisher, Kandice K Ludwig, Rachel M Danforth, R Jason VonDerHaar, Ravinder Bamba, Mary E Lester and 1 more

Abstract read
In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Abbas M HassanDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
John P HajjDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
John P LewisDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Shahnur AhmedDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Carla S FisherDivision of Breast Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Kandice K LudwigDivision of Breast Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Rachel M DanforthDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
R Jason VonDerHaarDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Ravinder BambaDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Mary E LesterDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
Aladdin H HassaneinDivision of Plastic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. ahassane@iu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer-related lymphedema (BCRL) significantly affects quality-of-life after axillary lymph node dissection (ALND). Although immediate lymphatic reconstruction (ILR) may reduce BCRL incidence, its long-term outcomes and predictors remain unclear. We report long-term BCRL prevalence in patients undergoing ILR and delineate factors associated with BCRL after ILR.

methodsWe retrospectively studied consecutive patients who underwent ILR following ALND between 2017 and 2024 across six hospitals in the Indiana University network. Primary outcome was BCRL prevalence, defined as ≥ 2-cm limb difference at two contiguous points. Secondary outcomes included BCRL predictors, postoperative complications, and compression garment use.

resultsWe identified 172 patients with a mean age 50.9 ± 11.6 years, body mass index of 29.5 ± 6.9 kg/m

conclusionsImmediate lymphatic reconstruction following ALND demonstrated low BCRL rates, although Black or African American patients remain at disproportionately higher risk, warranting targeted interventions and further investigation.

Indexed as

Breast NeoplasmsLymphedemaLymph Node ExcisionMammaplastyPostoperative ComplicationsAdultAgedAxillaFemaleFollow-Up StudiesHumansMastectomyMiddle AgedPrognosisQuality of LifeRetrospective StudiesBreast cancerILRLymphaLymphedema

Identifiers

PMID40238065
PMCPMC12222251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.