Evidence map›Paper›PMID 40238051›Full record

ArticleForensic science, medicine, and pathology2025

A rare case of lethal lactic acid poisoning: an autopsy case report.

Deepu Mathew, Keerthi Kumaran, Alagarasan Naveen, Ambika Prasad Patra, Pampa Ch Toi

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Article in Forensic science, medicine, and pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Deepu MathewDepartment of Forensic Medicine and Toxicology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantari Nagar, Puducherry, 605006, India.ORCID http://orcid.org/0009-0005-4207-9778
Keerthi KumaranDepartment of Forensic Medicine and Toxicology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantari Nagar, Puducherry, 605006, India.
Alagarasan NaveenDepartment of Forensic Medicine and Toxicology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantari Nagar, Puducherry, 605006, India. drnaveen358@gmail.com.ORCID http://orcid.org/0000-0003-2739-6861
Ambika Prasad PatraDepartment of Forensic Medicine and Toxicology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantari Nagar, Puducherry, 605006, India.
Pampa Ch ToiDepartment of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Dhanvantari Nagar, Puducherry, 605006, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More than 700,000 people die due to suicide every year, and ingestion of pesticides, hanging, and firearms are among the most commonly used suicide methods globally. Although corrosives are among the least preferred agents for suicide due to the extreme pain caused and the possibility of prolonged suffering instead of immediate death, cases of ingestion continue to be observed. Commonly ingested corrosive substances include acids such as hydrochloric and sulfuric acid, alkalis such as sodium and potassium hydroxide, heavy metal salts, formalin, and iodine tincture. However, previous literature has not reported cases of poisoning with lactic acid preparations in adults. In this report, we discuss the death of a 67-year-old male following the consumption of Lactisan, a commercial preparation of lactic acid used in the dairy industry. The diagnosis and management of lactic acid poisoning pose challenges due to the lack of any previous data and the short half-life of lactic acid in the bloodstream. The laboratory investigation showed severe lactic acidosis. We discuss in detail the gross and microscopic features of lactic acid poisoning. This case report emphasizes the need for awareness among healthcare professionals about such uncommon but potentially fatal poisonings.

Indexed as

Acidosis, LacticLactic AcidSuicide, CompletedAgedHumansMaleLactic AcidAcid ingestionAutopsy diagnosisCorrosive poisoningLactic acid poisoningToxicology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.