Observational studyAnnals of cardiac anaesthesia2025
Intraoperative Transesophageal Echocardiography Quantification of Mitral Regurgitation by Regurgitation Volume and Fraction Using 2D and 3D Techniques.
Observational study in Annals of cardiac anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Intraoperative Quantification of Severe Mitral Regurgitation: A Comparative Assessment of Two-Dimensional Flow Convergence, Three-Dimensional Volumetric, and Doppler-Based Methods.Journal of cardiovascular development and disease · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsIntraoperative quantification of mitral regurgitation (MR) is sometimes necessary to quantify the severity of incidentally detected MR during cardiac surgeries. We aimed to compare and correlate the regurgitant volume (Rvol) and regurgitant fraction (RF) using 2D proximal isovelocity surface area (PISA) and 3D vena contracta area (VCA) with the 3D volumetric method and the integrated multiparametric approach. METHODS AND MATERIALS: A prospective observational study was conducted on 37 patients undergoing mitral valve surgery for MR. Intraoperative quantification of the severity of MR was done using 2D PISA and 3D VCA methods and was compared with the 3D volumetric method. All three methods were compared with the integrated multiparametric method to obtain cutoff values for identifying severe MR.
resultsThe correlation coefficients for Rvol with VCA and PISA with the 3D volumetric method were 0.688 and 0.58, respectively. VCA and PISA overestimated the Rvol (VCA = 77.93 ± 27.82 ml, PISA = 76.13 ± 19.25 ml) compared to the 3D volumetric method (66.12 ± 20.30 ml); the RF by the three methods was comparable. Using the receiver operating characteristic-area under curve (AUC) comparing Rvol by these methods with the integrated multiparametric method, the 3D volumetric method performed the best.
conclusionThe Rvol VCA and PISA overestimated MR severity compared to the 3D volumetric method with moderate to good correlation. Rvol 3D was superior with a higher AUC when compared with the integrated multiparametric approach. The RF by the three methods was comparable, albeit with a higher threshold in quantifying severity compared to the conventional criteria.
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