Evidence map›Paper›PMID 40237452›Full record

ArticlemSystems2025

Genomic analysis and therapeutic efficacy evaluation of bacteriophage PK2420 for pneumonia caused by hypervirulent

Jinfeng Chen, Junxia Feng, Xiaohu Cui, Lijuan Huang, Bing Du, Yuyan Xia, Guanhua Xue, Yanling Feng, Yuehua Ke, Hanqing Zhao and 15 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Phage therapy againstFrontiers in microbiology · 2026
    Review
  5. Phage and endolysin-based inhibition ofFrontiers in cellular and infection microbiology · 2026
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Jinfeng Chen *Capital Institute of Pediatrics-Peking University Teaching Hospital, Beijing, China.ORCID 0009-0003-1627-2430
Junxia Feng *Department of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Xiaohu Cui *Department of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Lijuan HuangDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Bing DuDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Yuyan XiaDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Guanhua XueDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Yanling FengDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Yuehua KeDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Hanqing ZhaoDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Jinghua CuiDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Chao YanDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Lin GanDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.ORCID 0000-0003-2112-4689
Zheng FanDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Tongtong FuDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Ziying XuDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Yang YangDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Zihui YuDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Shuo ZhaoDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Zhen WangDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Yiming KongDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Boyi JiangDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Mingxuan WangDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Mengyao LingDepartment of Bacteriology, Capital Institute of Pediatrics, Beijing, China.
Jing YuanCapital Institute of Pediatrics-Peking University Teaching Hospital, Beijing, China.ORCID 0000-0002-6939-9676

Funding

Beijing High-Level Public Health Technical Talent Project 2023-02-08Beijing Hospitals Authority's Ascent Plan DFL20241301Beijing Municipal Public Welfare Development and Reform Pilot Project for Medical Research Institutes JYY2023-10Capital Health Research and Development of Special Fund 2024-4-1137National Natural Science Foundation of China 32170201National Natural Science Foundation of China 82130065National Natural Science Foundation of China 82302540National Natural Science Foundation of China 82372270Natural Science Foundation of Beijing Municipality 7222014Natural Science Foundation of Beijing Municipality 7242015
6 · The paper itself

Abstract

Hypervirulent

Indexed as

BacteriophagesKlebsiella InfectionsKlebsiella pneumoniaePhage TherapyPneumonia, BacterialAnimalsDisease Models, AnimalFemaleGenome, ViralGenomicsMiceSerogroupVirulencebacteriophage therapyhypervirulent Klebsiella pneumoniaeK20 serotype

Identifiers

PMID40237452
PMCPMC12090786

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.