Evidence map›Paper›PMID 40236951›Full record

ArticleClinical kidney journal2024

Achievement of fluid removal targets during intermittent renal replacement therapy in the intensive care unit.

Michel Gouin, Rose Joyal, Mathilde Lamothe, Yi Hui Luo, Xin Yi Fan, Karel Huard, Jean-Maxime Côté, Javier A Neyra, Ron Wald, William Beaubien-Souligny

Abstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michel GouinFaculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Rose JoyalFaculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Mathilde LamotheFaculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Yi Hui LuoFaculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Xin Yi FanFaculté de Médecine, Université de Montréal, Montreal, Quebec, Canada.
Karel HuardDepartment of Medicine, McGill University, Montreal, Quebec, Canada.
Jean-Maxime CôtéService of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0002-3487-2670
Javier A NeyraDepartment of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA.
Ron WaldDivision of Nephrology, St. Michael's Hospital, University of Toronto, Li Ka Shing Knowledge Institute, Toronto, ON, Canada.
William Beaubien-SoulignyService of Nephrology, Department of Medicine, Centre Hospitalier de l'Université de Montréal (CHUM), Montreal, Quebec, Canada.ORCID https://orcid.org/0000-0003-3030-8703

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In patients with acute kidney injury (AKI), fluid balance management often relies on the prescription and achievement of fluid removal using intermittent renal replacement therapy (IRRT). This study aimed to describe characteristics associated with the failure to achieve target fluid removal (FATFR). Methods: This is a retrospective cohort study including IRRT sessions of conventional duration (<5 hours) performed for AKI in the intensive care unit (ICU) from 2017 to 2022 at a tertiary academic center. FATFR-50% was defined as fluid removal of <50% of the prescribed target. Characteristics of patients and sessions, as well as outcomes at 90 days were collected. The causes of FATFR were manually adjudicated. Results: A total of 291 patients and 1280 IRRT sessions in the ICU were included. FATFR-50% occurred in 7.3% of sessions and 19.2% of patients had at least one session with FATFR-50% during the first week of IRRT. Sessions with FATFR-50% were characterized by a higher occurrence of intradialytic hypotension (24.2% vs 60.2%, Conclusions: FATFR occurs in about one out of five critically ill patients within the first week of IRRT and is associated with adverse clinical outcomes.

Indexed as

acute kidney injuryfluid overloadintermittent hemodialysisrenal replacement therapyultrafiltration

Identifiers

PMID40236951
PMCPMC11997759

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.