Evidence map›Paper›PMID 40236826›Full record

ArticleFrontiers in physiology2025

Using

Edward T Ashworth, Ryotaro Ogawa, David R Vera, Peter Lindholm

Abstract read
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Edward T AshworthDepartment of Emergency Medicine, University of California, San Diego, CA, United States.
Ryotaro OgawaDepartment of Radiology, University of California, San Diego, CA, United States.
David R VeraDepartment of Radiology, University of California, San Diego, CA, United States.
Peter LindholmDepartment of Emergency Medicine, University of California, San Diego, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Decompression sickness (DCS) during extravehicular activity in space or after diving is caused by gaseous nitrogen. The pathophysiology is still not fully understood, as mechanisms of dissolved gas uptake and bubble development are challenging to study. We aimed to develop a new method using nitrogen-13 ( Methods: A single anesthetized and ventilated Sprague Dawley rat lay supine inside a PET scanner for 30 min. The rat breathed oxygen for the first 2 min, then Results: The signal intensity in the PET scanner increased from baseline (0.03) to 2-12 min (0.68 ± 0.31), and 12-22 min (0.88 ± 0.06), before reducing slightly from 22 to 30 min (0.61 ± 0.04). All organs had radioactivity when measured in the gamma counter. We confirmed that the gas decayed radioactivity in expectance with the half-life of Discussion: This study successfully demonstrated a quantitative method of tracking nitrogen gas through the body both

Indexed as

decompression sicknessdivingextravehicular activityhyperbaric medicineradiolabeling

Identifiers

PMID40236826
PMCPMC11996788

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.