Trial reportDepression and anxiety2025
Brain Structural and Functional Neuroimaging Features are Associated With Improved Auditory Hallucinations in Patients With Schizophrenia After Real-Time fMRI Neurofeedback.
Trial report in Depression and anxiety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Real-time fMRI neurofeedback modulates auditory cortex activity and connectivity in schizophrenia patients with auditory hallucinations: A controlled study.Psychiatry research. Neuroimaging · 2025Trial
- Cognitive Impairment in Schizophrenia Across Different Clinical Manifestations and Its Association With Symptom Severity and Functional Status.Brain and behavior · 2026Article
- Targeting Network Imbalance in Schizophrenia: The Application of Temporal Interference Stimulation.Alpha psychiatry · 2026Article
- Decreased Broca-left supplementary motor area connectivity underlying auditory verbal hallucination: A resting-state NIRS study.Translational psychiatry · 2026Article
- NeuroMark-DyFICA: NeuroMark dynamic frequency-informed ICA with high-frequency spatial filtering for windowed fMRI analysis.Network neuroscience (Cambridge, Mass.) · 2026Article
- "Phantasia" in ICU: emulating to clarify ketamine's impact.Intensive care medicine · 2025Article
- Meditation and neurofeedback: A systematic scoping review, synthesis, and future directions.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Auditory hallucinations (AHs) are debilitating and often treatment-resistant symptoms of schizophrenia (SZ). Real-time functional magnetic resonance imaging (fMRI) neurofeedback (NFB) is emerging as a flexible brain circuit-based tool for targeting AH via self-modulation of brain activity. A better understanding of what baseline characteristics predict NFB success will enhance its clinical utility. Previous work suggests that AH symptomology implicates measures across multiple modalities, including T1 structural MRI (sMRI), diffusion-weighted MRI (dMRI), and resting-state fMRI (rsfMRI). Specifically, AH severity and treatment response are associated with thinner superior temporal gyrus (STG), thinner dorsolateral prefrontal cortex (DLPFC), reduced white matter integrity in tracts connecting brain regions implicated in SZ symptomatology, increased within-default mode network (DMN) connectivity, and reduced DMN-DLPFC anticorrelation. In this study, we tested the individual and combined contributions of multimodal brain features for the prediction of AH change after NFB in adults (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.