Evidence map›Paper›PMID 40236504›Full record

ReviewHemaSphere2025

Delving deeper into the pathogenesis and genomics of posttransplant diffuse large B-cell lymphoma.

Flore Sneyers, Ana-Lucía Rocha-Iraizos, Vibeke K J Vergote, Daan Dierickx

Abstract readReview
In one paragraph

Review in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Flore SneyersDepartment of Oncology Laboratory of Experimental Hematology KU Leuven Leuven Belgium.
Ana-Lucía Rocha-IraizosDepartment of Oncology Laboratory of Experimental Hematology KU Leuven Leuven Belgium.
Vibeke K J VergoteLeuven Kankerinstituut (LKI), KU Leuven - UZ Leuven Leuven Belgium.
Daan DierickxDepartment of Oncology Laboratory of Experimental Hematology KU Leuven Leuven Belgium.ORCID 0000-0002-8917-022X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posttransplant lymphoproliferative disorders (PTLDs) are a well-known complication of solid organ transplantation and allogeneic hematopoietic stem cell transplantation. The diffuse large B-cell lymphoma subtype (PT-DLBCL) is the most frequent monomorphic PTLD and is associated with poor prognosis. Transplant recipients have an increased risk of abnormal proliferation of lymphoid cells because of diminished immune surveillance. In about 60% of the cases, Epstein-Barr virus infection seems to contribute to the cancer phenotype. Although clinical and research interest in the disorder has increased during the last two decades, the pathology of the disease remains largely elusive. In this review, we summarize current knowledge of PT-DLBCL pathogenesis, and we discuss how a better understanding of PT-DLBCL can lead to improved diagnostics and therapeutic strategies.

Identifiers

PMID40236504
PMCPMC11997454

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.