ArticlemedRxiv : the preprint server for health sciences2025
Wastewater surveillance reveals patterns of antibiotic resistance across the United States.
Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Antibiotic resistance is a growing public health threat, with over 2.8 million antibiotic-resistant infections and 35,000 attributable deaths annually in the U.S. This is an underestimate, as it is based on people who seek medical attention. Here, we sought to use wastewater monitoring to assess community-level antibiotic resistance. This study quantifies concentrations of antibiotic resistance genes (ARGs) by digital droplet PCR in wastewater solids obtained from 163 wastewater treatment plants across the United States. We measure 11 ARGs that confer resistance to beta-lactams (
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