Evidence map›Paper›PMID 40235931›Full record

ReviewFrontiers in cellular and infection microbiology2025

Exploring urinary microbiome: insights into neurogenic bladder and improving management of urinary tract infections.

Jinming Zhang, Yingyun Lei, Huayong Du, Zehui Li, Xiaoxin Wang, Degang Yang, Feng Gao, Jianjun Li

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. The Urinary Microbiota and the Gut-Bladder Axis in Bladder Cancer.International journal of molecular sciences · 2025
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinming ZhangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Yingyun LeiSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Huayong DuSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Zehui LiSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Xiaoxin WangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Degang YangSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Feng GaoSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.
Jianjun LiSchool of Rehabilitation Medicine, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The traditional view of sterile urine has been challenged by advancements in next-generation sequencing, revealing that the urinary microbiome significantly influences individual health and various urinary system diseases. Urinary tract infections in patients with neurogenic bladder are highly prevalent, recurrent, and lifelong. If frequent urinary tract infections are not adequately managed, they may ultimately lead to chronic renal failure. The excessive use of antibiotics to prevent and treat urinary tract infections may lead to increased bacterial resistance, limiting future therapeutic options. This review summarizes commonly used microbiome research techniques and urine collection methods, compiles current studies on the urinary microbiome in neurogenic bladder patients, and discusses the potential implications of urinary microbiome composition for preventing, diagnosing, and treating urinary tract infections. By summarizing current research findings, we aim to enhance understanding of the urinary microbiome in neurogenic bladder patients and promote the standardization and clinical translation of microbiome research.

Indexed as

MicrobiotaUrinary Bladder, NeurogenicUrinary TractUrinary Tract InfectionsUrineAnti-Bacterial AgentsHumansAnti-Bacterial Agentsdiagnosticsmicrobiomeneurogenic bladdertreatmenturinary tract infectionsurine

Identifiers

PMID40235931
PMCPMC11996777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.