Evidence map›Paper›PMID 40235819›Full record

ReviewQuantitative imaging in medicine and surgery2025

Ultrasound cut-off values for muscle thickness, cross-sectional area, and echo intensity in Caucasian adults: a narrative review.

Jona Van den Broeck, Savanah Héréus, Erik Cattrysse, Hubert Raeymaekers, Aldo Scafoglieri

Abstract readReview
In one paragraph

Review in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jona Van den BroeckExperimental Anatomy Research Group, Department of Physiotherapy and Human Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-1648-0788
Savanah HéréusExperimental Anatomy Research Group, Department of Physiotherapy and Human Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-8639-1545
Erik CattrysseExperimental Anatomy Research Group, Department of Physiotherapy and Human Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0003-4325-9576
Hubert RaeymaekersDepartment of Radiology, University Hospital Brussels, Brussels, Belgium.ORCID https://orcid.org/0000-0003-0041-6359
Aldo ScafoglieriExperimental Anatomy Research Group, Department of Physiotherapy and Human Anatomy, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.ORCID https://orcid.org/0000-0002-9692-9513

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: The aging process is accompanied by the loss of muscle mass. Ultrasound emerges as promising, although, ultrasound routine screening for low muscle mass is challenging due to the lack of reference values. This review presents a comprehensive overview of cut-off values for predicting and diagnosing low muscle mass and quality. Methods: We used PubMed, Web of Science, and Scopus databases to gather pertinent articles up until April 2024. The quality of the articles was screened with the Pretorius and Keating [2008] assessment questionnaire. Our aim was to identify articles that assessed cut-off values for skeletal muscle thickness, cross-sectional area (CSA), and echo intensity using ultrasound in Caucasian adults. Key Content and Findings: This review incorporates thirteen articles of high quality and four of moderate quality. Fifteen articles investigated cut-off values for muscle thickness of muscles in the arms, legs, and trunk. Four studies reported CSA cut-off values, and only two studies provided echo intensity cut-off values. It appears that the cut-off values are influenced by participant characteristics, the ultrasound measurement method, and the statistical method that is used to assess the cut-off value. Conclusions: This review represents an overview of muscle cut-off values for diagnosing conditions such as sarcopenia and low muscle mass. The most studied and useful cut-off values pertain to the muscle thickness measurements of the gastrocnemius, quadriceps, rectus abdominis, and tibialis anterior muscles.

Indexed as

cut-off valuesmuscle echo intensitymuscle thicknessreferences valuesUltrasound

Identifiers

PMID40235819
PMCPMC11994489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.