ArticleQuantitative imaging in medicine and surgery2025
Left-atrioventricular interaction and left-atrial deformation in patients with type 2 diabetes mellitus with or without chronic aortic regurgitation: a 3.0-T cardiac magnetic resonance feature-tracking study.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Cardiac magnetic resonance biomarkers for cardiovascular complications in diabetes: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
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8 authors.
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Abstract
Background: The prevalence of type 2 diabetes mellitus (T2DM) and chronic aortic regurgitation (AR) increases with age and may also increase cardiac morbidity and mortality; however, their comprehensive effects based on cardiac strain remain unexplored. This study aimed to use cardiac magnetic resonance (CMR) feature tracking to investigate the additive effects of T2DM and AR on the left heart and left-atrioventricular interaction in patients with T2DM and AR. Methods: A total of 286 patients with T2DM (203 without AR and 83 with AR) and 105 controls were retrospectively included from January 2015 to October 2022. The patients with T2DM and AR were divided according to echocardiographic findings into three AR groups: mild (n=39), moderate (n=25), and severe (n=19). The left-atrial (LA) phasic function and left-ventricular (LV) function parameters were compared to determine the additive effects of T2DM and AR and their interaction. Multivariate analysis was performed to identify the independent indicators of LA longitudinal strain. Results: Compared with controls, the patients with T2DM without AR had a lower total LA emptying fraction (LAEF) and passive LAEF (all P values <0.05). The patients with T2DM and mild AR showed decreased LA reservoir strain (ε Conclusions: AR may aggravate LA and LV dysfunction in patients with T2DM. Regurgitation degree was an independent factor contributing to ε
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