Evidence map›Paper›PMID 40235790›Full record

ArticleQuantitative imaging in medicine and surgery2025

Magnetic resonance diffusion tensor imaging is superior to arterial spin labeling in detecting renal allograft fibrosis.

Jiayi Wan, Minmin Jin, Jie Li, Jiali Ma, Chenqin Que, Bin Jiang, Yangyang Tian, Linkun Hu, Yixing Yu, Chunhong Hu and 2 more

Abstract read
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Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Jiayi Wan *Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Minmin Jin *Department of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jie LiSuzhou Medical College of Soochow University, Suzhou, China.
Jiali MaDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chenqin QueXuzhou Medical University, Xuzhou, China.
Bin JiangDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yangyang TianDepartment of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Linkun HuDepartment of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Yixing YuDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Chunhong HuDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jun WangDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.
Mo ZhuDepartment of Radiology, The First Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although both magnetic resonance (MR) diffusion tensor imaging (DTI) and arterial spin labeling (ASL) have been demonstrated to be useful for the assessment of renal allograft fibrosis, their diagnostic value for renal allograft fibrosis is rarely compared. In this study, we collected a relatively large sample size to compare the value of DTI and ASL in the assessment of renal transplantation (RT) fibrosis. Methods: This study included 141 kidney transplant recipients who underwent DTI, ASL, and biopsy. The renal allograft fibrosis was divided into ci0, ci1, ci2, and ci3 fibrosis groups according to the biopsy results. The apparent diffusion coefficient (ADC), fractional anisotropy (FA), and renal blood flow (RBF) were calculated. One-way analysis of variance (ANOVA) was used to compare the differences of functional magnetic resonance imaging (MRI) parameters between different fibrosis subgroups. The area under the receiver operating characteristic curve (AUC) was calculated to evaluate diagnostic performance. Results: The medullary FA values in ci2 (0.27±0.04, P<0.001) and ci3 (0.21±0.03, P<0.001) groups were significantly lower than those in ci0 group (0.31±0.05). The medullary FA value in ci3 group (0.21±0.03) was significantly lower than that in ci1 group (0.30±0.07, P<0.001) and ci2 group (0.27±0.04, P<0.01). The AUC of DTI was found to be higher than that of ASL in accurately identifying renal allograft fibrosis, and the result was statistically significant in differentiating ci0-2 group and ci3 group (ci0 Conclusions: DTI has a higher diagnostic value than ASL in noninvasive identification of the degree of renal allograft fibrosis.

Indexed as

diffusionfibrosisperfusionRenal transplantation (RT)

Identifiers

PMID40235790
PMCPMC11994526

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.