Evidence map›Paper›PMID 40235777›Full record

ArticleQuantitative imaging in medicine and surgery2025

Short-term changes in myocardial perfusion of the predominant donor vessel after percutaneous coronary intervention for chronic total occlusion.

Wei Gao, Fan Fan, Guobing Liu, Hao Lu, Rende Xu, Kang Yao, Shuguang Chen, Feng Zhang, Shufu Chang, Yuxiang Dai and 6 more

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Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

16 authors.

Wei Gao *Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Fan Fan *Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Guobing Liu *Department of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Hao LuDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Rende XuDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Kang YaoDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Shuguang ChenDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Feng ZhangDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Shufu ChangDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Yuxiang DaiDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Jianying MaDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Lei GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Juying QianDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Hongcheng ShiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Chenguang LiDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It remains unclear how rapidly the collateral circulation regresses after percutaneous coronary intervention (PCI) of chronic total occlusion (CTO). This study aimed to investigate the short-term changes of myocardial perfusion in the predominant donor vessel after successful CTO PCI. Methods: A total of 68 patients who underwent single-photon emission computerized tomography (SPECT) assessment before and within 24-72 hours after successful CTO PCI were retrospectively included into this study. The coronary flow reserve (CFR) in the CTO territory and the predominant donor vessel territory were analyzed. Results: The average age of the included patients was 57.1±12.5 years old, and 88.2% were male. In the CTO territory, the CFR increased from 1.80±0.99 at baseline to 2.13±1.02 after PCI (P=0.018). In the predominant donor territory, the CFR at baseline did not significantly differ from that of after PCI (baseline: 2.12±1.09; after-PCI: 2.27±0.78; P=0.214). However, the change in CFR (ΔCFR) of the predominant donor territory was correlated with that in the CTO territory (P<0.001). The target vessel of CTO [left anterior descending artery (LAD) Conclusions: The myocardial perfusion in the predominant donor territory was positively associated with that in the CTO territory. The myocardial perfusion in the predominant donor territory increased within a short-term period after CTO PCI, specifically in those patients with CTO of the LAD.

Indexed as

Chronic total occlusion (CTO)myocardial perfusion imaging (MPI)percutaneous coronary intervention (PCI)predominant donor vesselsingle-photon emission computerized tomography (SPECT)

Identifiers

PMID40235777
PMCPMC11994573

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