ArticleQuantitative imaging in medicine and surgery2025
Peak regurgitant diastolic wall shear stress increases in bicuspid aortic valve regurgitation: association of regurgitation severities and aortic root dilation.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Real-time three-dimensional echocardiographic assessment of the association between aortic diameter and left ventricular mechanical dyssynchrony in patients with bicuspid aortic valve.Quantitative imaging in medicine and surgery · 2026Article
- Post-valvular energy exchange in bicuspid aortic valve with regurgitation and stenosis and its association with left ventricular workload: a 4D flow magnetic resonance imaging cross-sectional study.BMC medical imaging · 2025Article
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Authors and funding
5 authors.
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Abstract
Background: Bicuspid aortic valve (BAV) disease, especially with regurgitation, lacks adequate clinical management. While root aortopathy is often attributed to genetic factors and aortic regurgitation, the diastolic hemodynamic characteristics in BAV patients with varying regurgitation severities are not well understood. Flow-derived velocity-weighted flow displacement (FD) and wall shear stress (WSS) are linked to aortopathy progression. We sought to evaluate peak systolic and peak regurgitant diastolic regional WSS and FD at the aortic root in BAV patients with regurgitation (BAV-REG) and BAV patients without or with trivial regurgitation (BAV-No/Trivial REG). Methods: To conduct this retrospective study, a total of 98 subjects (N=38 BAV-No/Trivial REG, age: 48±16 years, N=35 BAV-REG, age: 52±13 years, and N=25 healthy, age: 38±14 years) were recruited. All subjects underwent routine cardiac magnetic resonance imaging (MRI) followed by four-dimensional cardiovascular magnetic resonance flow imaging using a 3.0 Tesla MRI scanner. Regional peak systolic (WSS Results: BAV-REG had similar planar WSS Conclusions: Higher WSS
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