ArticleQuantitative imaging in medicine and surgery2025
Evaluation of liver function using hepatocyte uptake and T1 mapping indices in gadoxetic acid-enhanced magnetic resonance imaging: correlation with the albumin-bilirubin grading system.
Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- MRI-Derived Evaluation of Liver Function and Its Extension to K-Edge Photon-Counting CT: Focus on Gadolinium-Based Functional Biliary Imaging.Diagnostics (Basel, Switzerland) · 2026Review
- Beyond morphology: functional imaging of the liver with gadoxetic acid-enhanced magnetic resonance imaging.Abdominal radiology (New York) · 2026Review
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10 authors.
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Abstract
Background: Assessing liver function is crucial for managing chronic liver diseases. This study aimed to evaluate the efficacy of hepatocyte uptake and the longitudinal relaxation time (T1) mapping indices from gadoxetic acid-enhanced magnetic resonance imaging (MRI) for evaluating liver function and its correlation with the albumin-bilirubin (ALBI) grading system. Methods: We retrospectively studied 183 patients who were grouped based on ALBI score: normal liver function (NLF), ALBI 1, ALBI 2, and ALBI 3. We calculated T1 indices and analyzed their correlation with ALBI grade, and differences among ALBI groups were evaluated. Receiver operating characteristic curves were used to assess the discriminative power of hepatocyte uptake and T1 indices for liver function groups, with significance set at P<0.05. Results: Significant differences were observed in hepatocyte uptake and T1 indices across the NLF and ALBI groups (P<0.001). T1 value before enhancement (T1pre), T1 value after enhancement (T1post) prolonged, and rate of decrease in the T1 relaxation time (ΔT1), hepatocyte uptake rate (K Conclusions: K
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