Evidence map›Paper›PMID 40235737›Full record

ArticleQuantitative imaging in medicine and surgery2025

Fetal heart quantification ultrasound technology for the quantitative analysis of fetal cardiac morphology and function in hypertensive disorders of pregnancy.

Yao Peng, Wei Feng, Chang-Xiu Yu, Cai-Hong Chang, Xue Liao, Ling Gan, Jia-Qi Zhang

Abstract read
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Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yao Peng *Department of Ultrasound Imaging, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, China.ORCID https://orcid.org/0009-0004-1305-4558
Wei Feng *Hubei Provincial Clinical Research Center for Accurate Fetus Malformation Diagnosis, Department of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Chang-Xiu YuHubei Provincial Clinical Research Center for Accurate Fetus Malformation Diagnosis, Department of Ultrasound, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Cai-Hong ChangDepartment of Ultrasound Imaging, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, China.
Xue LiaoDepartment of Ultrasound Imaging, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, China.
Ling GanDepartment of Ultrasound Imaging, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, China.
Jia-Qi ZhangDepartment of Ultrasound Imaging, Postgraduate Union Training Base of Xiangyang No. 1 People's Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, China.ORCID https://orcid.org/0000-0003-2234-1730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertensive disorders of pregnancy (HDP) are associated with adverse outcomes for both the mother and fetus, including impaired fetal cardiac development and function. Accurate assessment of fetal heart morphology and function is essential for the early detection and management of potential complications. This study investigated the clinical application value of fetal heart quantification (Fetal HQ) technology in evaluating the cardiac morphology and function in fetuses from pregnancies affected by HDP. Methods: This prospective study examined 43 fetuses from singleton pregnancies complicated by HDP [mean gestational age (GA) 29.5±2.8 weeks] and 50 fetuses from normal pregnancies (mean GA 29.2±2.4 weeks). All participants underwent fetal ultrasonography from August 2023 to July 2024. Fetal HQ technology, incorporating two-dimensional speckle-tracking echocardiography (2D-STE) with quantitative analysis of cardiac segments, was used to assess heart size, shape, ventricular structure, contractility, and function. Results: The HDP group exhibited significantly altered maternal clinical characteristics, including higher maternal weight, BMI, and blood pressure. Fetal cardiac morphometry indicated that compared to the control group, the HDP group had larger left ventricular (LV) dimensions yet lower volumes but had smaller right ventricular (RV) dimensions. Notably, compared with the control group, the HDP group had a larger LV end-diastolic (ED) area (2.52±0.88 Conclusions: Fetal HQ technology effectively identified significant alterations in fetal heart structure and function in pregnancies complicated by HDP. These findings suggest that Fetal HQ is a useful tool for the early detection of fetal heart abnormalities and can facilitate timely intervention and accurate prognosis in affected pregnancies.

Indexed as

fetal cardiac functionfetal cardiac morphologyfetal heart quantification technology (Fetal HQ technology)Hypertensive disorders of pregnancy (HDP)ultrasound imaging

Identifiers

PMID40235737
PMCPMC11994513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.