Functional and structural organization of medial entorhinal cortex layer VI.

Märt Rannap, Shinya Ohara, Janis Winterstein, Fabian C Roth, Andreas Draguhn, Alexei V Egorov

Abstract read

In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Märt RannapInstitute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.

Shinya OharaLaboratory of Systems Neuroscience, Tohoku University Graduate School of Life Sciences, Sendai 980-8577, Japan.

Janis WintersteinInstitute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.

Fabian C RothDivision of Physiology, Department of Molecular Medicine, Institute of Basic Medical Sciences, University of Oslo, 0372 Oslo, Norway.

Andreas DraguhnInstitute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.

Alexei V EgorovInstitute of Physiology and Pathophysiology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep layers (V/VI) of the entorhinal cortex transfer hippocampal neuronal activity to downstream neocortical networks. In addition, neurons in layer VI (LVI) of the medial entorhinal cortex (MEC) project back to all hippocampal subregions and contribute to spatial coding and memory. Their role in the processing of hippocampal output signals and their interaction with LV neurons is, however, unknown. We show that spontaneously occurring hippocampal sharp wave-ripple complexes reliably propagate from area CA1 to MEC LVI. Using anterograde tracing and

Indexed as

Biological sciencesNatural sciencesNeuroscienceSystems neuroscience

Identifiers

PMID40235593

DOI10.1016/j.isci.2025.112207

PMCPMC11999471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.