Evidence map›Paper›PMID 40235540›Full record

ArticleFrontiers in pharmacology2025

Serdar Yigit, Sakir Akgun, Isa Yesilyurt, Soner Bitiktas, Ergin Taskin, Ali Alper Kahraman, Muhammed Yayla, Pınar Aksu Kilicle, Seyit Ali Bingol, Bengul Ozdemir and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Serdar YigitHistology and Embryology Department, Faculty of Medicine, Kafkas University, Kars, Türkiye.
Sakir AkgunKafkas University Department of Medical Biology, Faculty of Medicine, Kars, Türkiye.
Isa YesilyurtPhysıology Department, Kafkas University, Faculty of Medicine, Kars, Türkiye.
Soner BitiktasPhysıology Department, Kafkas University, Faculty of Medicine, Kars, Türkiye.
Ergin TaskinDepartment of Biochemistry, Faculty of Medicine, Ağrı İbrahim Çeçen University, Ağrı, Türkiye.
Ali Alper KahramanHistology and Embryology Department, Kafkas University, Kars, Türkiye.
Muhammed YaylaPharmacology Department, Faculty of Medicine, Selcuk University, Konya, Türkiye.
Pınar Aksu KilicleDepartment of Biology, Faculty of Sciences and Arts, Kars, Türkiye.
Seyit Ali BingolHistology and Embryology Department, Faculty of Medicine, Kafkas University, Kars, Türkiye.
Bengul OzdemirHistology and Embryology Department, Faculty of Medicine, Kafkas University, Kars, Türkiye.
Gül Esma AkdoganDepartment of Biology, Faculty of Sciences and Arts, Kars, Türkiye.
Mehmet Ali KaragözDepartment of Urology, Kafkas University, Kars, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The aim was to investigate the possible protective effect of Methods: A total of 56 male rats were divided in to 7 equal groups. Ischemia was induced by taking the testicles out of the scrotum and rotating them 720° and after 3 h reperfusion was induced. Results: Histopathologically, H&E staining showed disruption in the seminiferous tubule structure in the ischemia and IR groups SOD levels decreased significantly in the IR group compared to the control group, whereas Berberis vulgaris did not change SOD levels following IR at 300 and 600 mg/kg doses. At the dose of 600 mg/kg, Conclusion:

Indexed as

bcl-2Berberis vulgariscaspase-3ischemia and reperfusiontestes

Identifiers

PMID40235540
PMCPMC11996762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.