ArticleJoint diseases and related surgery2025
Frailty as a predictor of vertebral fractures in osteoporosis: A clinical perspective.
Article in Joint diseases and related surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between neutrophil to lymphocyte ratio and the risk of vertebral fracture in patients with osteoporosis: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Unmet Healthcare Needs and Associated Factors Among Older Adults with Osteoporosis: A Cross-Sectional Analysis of the 2025 Korea Community Health Survey.Healthcare (Basel, Switzerland) · 2026Article
- Frailty and sarcopenia as independent predictors of early functional recovery in older adults with osteoporotic vertebral compression fractures: a retrospective cohort study.Frontiers in nutrition · 2026Article
- The q-Dixon sequence for MRI predicts osteoporotic vertebral compression fractures.Frontiers in endocrinology · 2025Article
- Frailty and lived experiences in older adults with osteoporosis: protocol for a convergent mixed-methods study.Frontiers in medicine · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
objectivesThis study aims to assess the correlation between vertebral compression fractures (VCFs) and frailty and to identify the possible link between the number of VCFs and frailty intensity in patients with osteoporosis (OP). PATIENTS AND
methodsBetween January 2025 and February 2025, a total of 204 patients (143 males, 61 females; mean age: 71.8±5.5 years; range, 65 to 89 years) over 65 years who received treatment for OP in the inpatient setting were included. The patients were divided into two groups according to their Clinical Frailty Scale (CFS) scores as the frail group (n=141, CFS ≥4) and the non-frail group (n=63, CFS <4). Demographic and clinical characteristics, geriatric syndromes, and fracture prevalence were recorded.
resultsThe handgrip strength was significantly reduced in the frail group (19 kg vs. 21 kg, p=0.004), with a probable sarcopenia rate of 42% (p=0.034). The rate of participants with no fractures, a single fracture, and multiple fractures was 42%, 26%, and 22% in the non-frail group, compared to 57%, 73%, and 77% in the frail group, respectively (p=0.018). This difference was particularly evident in patients with multiple fractures (odds ratio [OR]=2.34, 95% confidence interval [CI]: 1.13-4.87, p=0.023).
conclusionFrailty is strongly associated with a higher incidence of VCFs and multiple fractures in older individuals with OP.
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