Evidence map›Paper›PMID 40235223›Full record

ArticleESC heart failure2025

Right atrial remodelling and prognosis in patients with severe atrial functional tricuspid regurgitation.

Soongu Kwak, Dong-Jae Han, Seung-Pyo Lee, Ho Young Hwang, Hyung-Kwan Kim, Yong-Jin Kim, Kyung Hwan Kim, Jae Woong Choi, Jun-Bean Park

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soongu KwakDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Dong-Jae HanDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Seung-Pyo LeeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Ho Young HwangDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Hyung-Kwan KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Yong-Jin KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kyung Hwan KimDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jae Woong ChoiDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jun-Bean ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0003-4053-8713

Funding

National Research Foundation of Korea RS-2024-00449868
6 · The paper itself

Abstract

aimsAtrial functional tricuspid regurgitation (AFTR) is increasingly recognized as a distinct cause of tricuspid regurgitation, yet data on outcomes and their determinants are limited. This study examines the prognostic role of right atrial (RA) remodelling in patients with severe AFTR. METHODS AND

resultsThis retrospective study included consecutive patients with severe AFTR. The primary outcome was all-cause mortality. Cutoff values for RA and right ventricular (RV) sizes related to mortality were identified using receiver operating characteristic curves and maximally selected rank statistics. The cohort included 155 patients with severe AFTR, 96.1% of whom had atrial fibrillation. Of these, 121 received medical treatment, and 34 underwent surgery during follow-up. In the medical management group, 42 deaths (34.7%) occurred over a median of 3.3 years. Patients with high RV end-diastolic area and RA area indices (>14.5 cm

conclusionsRA and RV enlargement are poor prognostic factors in patients with severe AFTR. These findings underscore the importance of assessing RA and RV remodelling to optimize the timing of intervention in this population.

Indexed as

Atrial Function, RightEchocardiographyTricuspid ValveTricuspid Valve InsufficiencyAgedAtrial FibrillationCardiac Surgical ProceduresFemaleHumansMaleRepublic of KoreaRetrospective StudiesMortalityRight atriumRight ventricleTricuspid regurgitation

Identifiers

PMID40235223
PMCPMC12287840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.