Evidence map›Paper›PMID 40235187›Full record

ArticleEarly intervention in psychiatry2025

Proof-of-Concept Pilot Study on the Integration of a Contingency Management Model to Address Substance Use Among Individuals Enrolled in Early Intervention Programs for Psychosis.

Oladunni Oluwoye, Megan Puzia, Bryony Stokes, Elizabeth R Fraser, Sheldon Stokes, Khairul Siddiqi, John M Roll

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Oladunni OluwoyeElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.ORCID 0000-0003-2743-1620
Megan PuziaElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
Bryony StokesElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
Elizabeth R FraserElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
Sheldon StokesElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
Khairul SiddiqiElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.
John M RollElson S. Floyd College of Medicine, Washington State University, Spokane, Washington, USA.

Funding

Mentoring Emerging Scientists for Careers in Substance Use ResearchR25DA035163 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Carmen L Masson, Gideon St.Helen · 2014 to 2026
$4.6M
NIDA NIH HHS R25 DA035163NIH HHS R25DA035163SAMHSA HHS B09SM087386
6 · The paper itself

Abstract

backgroundStudies have reported high rates of alcohol and cannabis use and poor outcomes associated with substance use among individuals enrolled in coordinated specialty care (CSC) for first episode psychosis (FEP). Given these findings, substance use interventions within CSC would likely benefit individuals with FEP. This proof-of-concept study tested a standard and family-based contingency management (CM) model within CSC.

methodFourteen participants were recruited from a CSC programme for FEP to participate in standard CM and family-based CM for substance use intervention developed and refined by an advisory board comprised of key stakeholders. The CM intervention consisted of personalising CM by allocating participants to receive standard CM or family-based CM. Participants submitted urinalysis samples to assess alcohol and cannabis use across a 2-week warm-up phase, followed by a 12-week active CM phase.

resultsApproximately 60% of participants identified as an ethnoracial minority. At baseline, 78% of participants reported cannabis as the primary target substance and 64% opted into the family-based model. Eighty-four percent of urinalysis samples were submitted and 64% completed ≥ 8 weeks. Compared to baseline, substance use significantly decreased during the active CM phase (p < 0.003).

conclusionsThis pilot study suggests that a flexible CM model to address alcohol and cannabis, with the option for family involvement, may be feasible in CSC settings and increase abstinence among young adults with FEP. A high percentage of urinalysis samples were submitted, although most participants completed less than 12 weeks of CM. While findings show promise, additional modifications and pilot studies are needed to further optimise CM for CSC prior to conducting a larger efficacy trial.

Indexed as

Behavior TherapyEarly Medical InterventionPsychotic DisordersSubstance-Related DisordersAdolescentAdultFemaleHumansMalePilot ProjectsProof of Concept StudyYoung Adultcontingency managementcoordinated specialty carepsychosissubstance use

Identifiers

PMID40235187
PMCPMC12000795

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.