Evidence map›Paper›PMID 40234904›Full record

ArticleEuropean journal of medical research2025

Association of hematological parameters and inflammatory indices with sarcopenia in the United States and China: a cross-sectional study.

Ying Cheng, Chen Kuang, Gang Zhang, Zhongzheng Zhang, Kunpeng Qin

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ying Cheng *Department of Rehabilitation Medicine, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei, 230022, Anhui, China.
Chen Kuang *Department of Joint Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, No. 388 Zuchongzhi Road, Kunshan, 215300, Jiangsu, China.
Gang ZhangDepartment of Rehabilitation, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, 100 Huaihai Dadao, Xinzhan District, Hefei, 230011, Anhui, China.
Zhongzheng ZhangDepartment of Rehabilitation, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, 100 Huaihai Dadao, Xinzhan District, Hefei, 230011, Anhui, China.
Kunpeng QinDepartment of Orthopaedics, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, 100 Huaihai Dadao, Xinzhan District, Hefei, 230011, Anhui, China. qkp200008@126.com.

Funding

Health Research Program of Anhui AHWJ2023A20394
6 · The paper itself

Abstract

backgroundIn this study, we examined the association between hematological parameters and inflammatory indices and sarcopenia in the general population of the United States and China.

methodsThe cross-sectional study was conducted using data from the National Health and Nutrition Examination Survey (NHANES) (2011-2014) and the Affiliated Hospital of Anhui Medical University (2022-2024). We employed weighted restricted cubic spline (RCS) plots and multivariable logistic regression analyses to explore the association of hematological parameters and inflammatory indices with the prevalence of sarcopenia in American and Chinese populations.

resultsA total of 8805 participants from NHANES, and 2598 individuals from the First Affiliated Hospital of Anhui Medical University were included in our analysis. In American and Chinese populations, the roughly J-shaped curve was detected in the RCS plots for mean platelet volume and platelet-to-lymphocyte ratio with the risk of sarcopenia. Additionally, the risk of sarcopenia was positively and linearly associated with white blood cells, lymphocytes and platelet, while it was inversely and linearly associated with mean cell volume.

conclusionsWe demonstrated a nonlinear association between some hematological parameters, inflammatory indices and sarcopenia in American and Chinese populations. The need to focus more on hematological parameters and inflammatory indices in the body could provide better prevention strategies for sarcopenia.

Indexed as

InflammationSarcopeniaAdultAgedChinaCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysPrevalenceUnited StatesAmerican populationChina populationCross-sectional studyInflammationSarcopenia

Identifiers

PMID40234904
PMCPMC12001666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.