Evidence map›Paper›PMID 40234889›Full record

ArticleBMC oral health2025

Risk correlates of cardiovascular diseases, diabetes, and periodontal diseases: a cross-sectional study in India.

Lakshmi Puzhankara, Chandrashekar Janakiram, Georg Gutjahr, Sandra Chaithanyam Bijukumar, Ramprasad Vasthare, Madhurya N Kedlaya, Sahana Shetty, Aparna Ramakrishna Pai, Sudhakar Rao, Sowmya Srinivasan and 1 more

Abstract read
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lakshmi PuzhankaraManipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Chandrashekar JanakiramAmrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, 682041, India. sekarcandra@gmail.com.
Georg GutjahrDepartment of Health Science Research, Amrita Institute of Medical Sciences and Research Center, Kochi, Kerala, India.
Sandra Chaithanyam BijukumarDepartment of Mathematics, Amrita Vishwa Vidyapeetham, Amritapuri, Kollam, Kerala, India.
Ramprasad VasthareManipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Madhurya N KedlayaManipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sahana ShettyKasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Aparna Ramakrishna PaiKasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Sudhakar RaoManipal Hospitals, Bengaluru, India.
Sowmya SrinivasanDepartment of Periodontics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.
Angel FenolDepartment of Periodontics, Amrita School of Dentistry, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuantifying shared risk factors among periodontal disease (PD), cardiovascular disease (CVD), type 2 diabetes (DM2) can bolster Common Risk Factor Approach (CRFA), enabling integration of PD prevention into non-communicable disease (NCD) prevention strategies. The objective of the study is to assess extent of overlap of shared risk factors between CVD, DM2, PD. MATERIALS AND

methodsThis is an analytical cross-sectional study conducted at a tertiary care medical and dental teaching hospital in South India, from July 2022 to April 2024. Study included 600 participants (ages 18-75) divided into three groups: Group A: DM2, CVD, or both and PD; Group B: DM2 or CVD; and Group C: PD alone. Various demographic, metabolic, habit related, dietary and periodontal disease severity related risk factors were evaluated in the study.

resultsAmong 600 participants, 55.5% were male, 58.8% were under 50 years. Statistically significant odds ratios (ORs) for shared risk factors between Group A and Group B were observed for age > 50 (0.58), sedentary lifestyle (0.43), fat intake > 41 g/d (1.87), HbA1C ≥ 6.5% (0.56), FBS > 126 mg/dL (2.35) and family history of NCDs (9.8). For Group A versus Group C, statistically significant ORs were seen for age > 50 (0.55), HbA1c 5.7%-6.4% (0.34), triglycerides > 150 mg/dL (0.04), education (0.52), alcohol use (1.53) and poor oral hygiene (3.01). Severity of periodontal disease assessed using PSR, HbA1c, triglycerides, fat intake, age, education, obesity were identified as vital shared risk factors. CONCLUSION AND RELEVANCE: Age, education, obesity, PSR, HbA1c, triglycerides emerged as significant shared risk factors. Integrating these factors into surveillance tools may enhance NCD and PD risk identification, supporting CRFA-based healthcare approach.

trial registrationCTRI/ 2022/06/043279 registered on 15th of June 2022.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Periodontal DiseasesAdolescentAdultAgedCross-Sectional StudiesFemaleGlycated HemoglobinHumansIndiaMaleMiddle AgedRisk FactorsYoung AdultGlycated HemoglobinDisease preventionHealth EquityIntegrated Health Care SystemsRisk adjustmentRisk FactorRisk reduction behaviour

Identifiers

PMID40234889
PMCPMC12001716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.