ArticleBMC public health2025
Association between chronic PM
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Review
- Atmospheric Aerosol Neurotoxicity and Parkinson's Disease: Mechanisms and Perspectives.Journal of biochemical and molecular toxicology · 2026Review
- Sex-specific associations between astrocytic reactivity and cognitive decline in unimpaired elderly.bioRxiv : the preprint server for biology · 2026Article
- Associations between air pollution and markers of neuroinflammation, synaptic dysfunction and core Alzheimer's disease pathology vary by APOE genotype.Neurotoxicity research · 2026Article
- Airborne particulate matter and the lung-brain axis: unraveling the neuroinflammatory cascade from alveolar irritation to microglial activation.Journal of neuroinflammation · 2026Review
- Alterations in neuroinflammatory and neurodegenerative biomarkers among long-term residents of a critically polluted area: a cross-sectional comparative study.Scientific reports · 2025Article
- Xenobiotic Toxicants and Particulate Matter: Effects, Mechanisms, Impacts on Human Health, and Mitigation Strategies.Journal of xenobiotics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundAir pollution is a significant public health concern, increasingly recognized for its association with adverse health outcomes including neurodegenerative and neuroinflammatory conditions. The present study aimed to characterize plasma levels of key biomarkers related to neurodegeneration and neuroinflammation among middle-aged to elderly adults living in areas designated as critically polluted.
methodsA total of 202 adults, aged 41 to 60 years, residing in CPA (CEPI > 70) for over ten years were recruited in the study. The exposures of air pollutant were measured as per the established protocols by CPCB. The plasma levels of neurodegenerative markers (Aβ
resultsThis study confirmed the elevated PM
conclusionThis study is among the first community-based investigations in India to assess plasma levels of neurodegenerative and neuroinflammatory biomarkers in apparently healthy adults chronically exposed to high ambient air pollution. By integrating chronic exposure data from a Critically Polluted Area (CEPI > 70) with biomarker profiling, the study offers early insights into potential neurobiological alterations associated with environmental pollutants, highlighting sex- and age-specific vulnerabilities. These findings emphasize the importance of considering environmental influences in neurodegenerative disease research and the potential need for tailored health interventions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.