Evidence map›Paper›PMID 40234851›Full record

Observational studyBMC pregnancy and childbirth2025

Comparative differences in metabolic, mental health and perinatal outcomes of women with gestational diabetes in Ghana and Switzerland: the G-MUM study.

Dan Yedu Quansah, Kelvin Yeboah, Floriane Schweitzer, Sandra Yedu Quansah, Evans Kofi Agbeno, Antje Horsch, Katrien Benhalima, A Kofi Amegah, Jardena J Puder

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Observational study in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Dan Yedu QuansahObstetric service, Department Woman-Mother-Child, Lausanne University Hospital, Rue du Bugnon 21, Lausanne, CH-1011, Switzerland. dan.quansah@chuv.ch.ORCID http://orcid.org/0000-0002-3091-9400
Kelvin YeboahPublic Health Research Group, Department of Biomedical Sciences, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.
Floriane SchweitzerObstetric service, Department Woman-Mother-Child, Lausanne University Hospital, Rue du Bugnon 21, Lausanne, CH-1011, Switzerland.
Sandra Yedu QuansahDepartment of Education and Psychology, University of Cape Coast, Cape Coast, Ghana.
Evans Kofi AgbenoDepartment of Obstetrics and Gynecology, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID http://orcid.org/0000-0003-1725-2944
Antje HorschInstitute of Higher Education and Research in Healthcare (IUFRS), University of Lausanne, Lausanne, Switzerland.ORCID http://orcid.org/0000-0002-9950-9661
Katrien BenhalimaDepartment of Endocrinology, UZ Gasthuisberg, KU Leuven, Leuven, Belgium.ORCID http://orcid.org/0000-0002-3325-0263
A Kofi Amegah *Public Health Research Group, Department of Biomedical Sciences, School of Allied Health Sciences, University of Cape Coast, Cape Coast, Ghana.ORCID http://orcid.org/0000-0001-5868-6402
Jardena J Puder *Obstetric service, Department Woman-Mother-Child, Lausanne University Hospital, Rue du Bugnon 21, Lausanne, CH-1011, Switzerland.ORCID http://orcid.org/0000-0002-0460-7614

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) prevalence (9-15%) is similar in Ghana and Switzerland, despite differences in sociodemographic characteristics, lifestyle, and healthcare systems. Contrary to Switzerland, data on the metabolic and mental health outcomes of women with GDM in Ghana is lacking. We compared the metabolic, mental health, and perinatal outcomes of GDM during pregnancy in Ghana and Switzerland.

methodsThis prospective observational study included 170 women with GDM from two cohorts (n = 88 in Switzerland, n = 82 in Ghana) who were followed-up until delivery. Primary outcomes were metabolic [HbA1c, gestational weight gain (GWG)], well-being (WHO-5), and depression symptoms (EPDS) during pregnancy. Secondary outcomes were obstetric and neonatal outcomes. Differences in metabolic, mental health and perinatal outcomes were tested using ANOVA, Chi-square test or ANCOVA when appropriate. For the perinatal outcomes, we adjusted for metabolic confounders.

resultsCompared to the Swiss cohort (SC), the Ghana cohort (GC) had a higher pre-pregnancy weight (79.8 ± 18.0 vs. 71.8 ± 15.3 kg, p = 0.003) and BMI (30.8 ± 6.6 vs. 26.5 ± 4.9 kg/m

conclusionWomen in the GC had worse metabolic outcomes but improved mental health during pregnancy. In this context, LGA and neonatal hospitalisations were higher, independent of HbA1c and pre-pregnancy BMI. Our results suggest the need for specialized GDM clinics in Ghana to improve metabolic and perinatal outcomes in women with GDM.

Indexed as

Diabetes, GestationalMental HealthAdultBody Mass IndexDepressionFemaleGestational Weight GainGhanaGlycated HemoglobinHumansInfant, NewbornPregnancyPregnancy OutcomePrevalenceProspective StudiesSwitzerlandGlycated Hemoglobinhemoglobin A1c protein, humanEating behaviourGhanaMental health, gestational diabetesMetabolicNeonatalObstetricSwitzerland

Identifiers

PMID40234851
PMCPMC11998157

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.