Evidence map›Paper›PMID 40234831›Full record

SynthesisBMC infectious diseases2025

COVID- 19 vaccine uptake and its determinants in Cameroon: a systematic review and meta-analysis (2021-2024).

Fabrice Zobel Lekeumo Cheuyem, Adidja Amani, Chabeja Achangwa, Brian Ngongheh Ajong, Claude Axel Minkandi, Myriam Mathilde Mbia Kouda Zeh, Larissa Linda Eyenga Ntsek, Jacques Philippes Essomba, Rudy Chiozem Jiogue, Olivier Ndagijimana and 2 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fabrice Zobel Lekeumo CheuyemDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon. zobelcheuyem@gmail.com.
Adidja AmaniDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Chabeja AchangwaDepartment of Public Health, Faculty of Medical Sciences, University of the West Indies, Cave Hill, Barbados.
Brian Ngongheh AjongHealth Emergencies Programme, World Health Organization (WHO), Kinshasa, Democratic Republic of Congo.
Claude Axel MinkandiNational Multisectoral Programme to Fight Against Maternal and Child Mortality, Yaounde, Cameroon.
Myriam Mathilde Mbia Kouda ZehDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Larissa Linda Eyenga NtsekDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Jacques Philippes EssombaDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Rudy Chiozem JiogueDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Olivier NdagijimanaDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Ndzi Etienne NchanjiDepartment of Public Health, Faculty of Medicine and Biomedical Sciences, The University of Yaounde I, Yaounde, Cameroon.
Celestin DanwangWorld Health Organization Regional Office for Africa, Brazzaville, Congo.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundCOVID-19 vaccination is crucial for mitigating the pandemic's impact. However, vaccine hesitancy and access challenges have hindered global vaccination efforts. This meta-analysis aimed to estimate the pooled COVID-19 vaccine uptake proportion and identify associated determinants in Cameroon.

methodsThis review, conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, identified articles through searches of electronic databases, including PubMed, ScienceDirect, and Google Scholar, as well as through gray literature. The search encompassed published and unpublished studies from 2021 to 2024 reporting on COVID-19 vaccine uptake and/or acceptance in Cameroon. Extracted data were compiled in a Microsoft Excel spreadsheet and analyzed using R statistical software (version 4.4.2). A random-effects model was employed when heterogeneity exceeded 50%. Publication bias was assessed using funnel plots, Egger's and Begg's tests. Meta-regression was used to explore the influence of study characteristics.

resultsTwenty-two studies, encompassing 24,130 participants, were included. The pooled vaccine uptake proportion was 37.14% (95% CI: 29.24-45.05) with substantial heterogeneity (I

conclusionThis meta-analysis revealed a suboptimal pooled COVID-19 vaccine uptake required to ensure a herd immunity. The results of this meta-analysis underline the crucial need to step up efforts to improve vaccination coverage, particularly among the most vulnerable populations. Identifying and addressing the factors underlying this low coverage is imperative if public health objectives are to be met. Public health interventions should be tailored to address the specific concerns and needs of different age groups and marital statuses.

Indexed as

COVID-19COVID-19 VaccinesVaccinationVaccination HesitancyAdultCameroonHumansSARS-CoV-2COVID-19 VaccinesAcceptanceCameroonCoverageCOVID- 19 vaccineHesitancyMeta-analysisRisk factorSystematic reviewUptake

Identifiers

PMID40234831
PMCPMC12001614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.