Evidence map›Paper›PMID 40234817›Full record

Trial reportBMC nephrology2025

Efficacy of the ALL YOU NEED IS LOVE healthcare transition syllabus among pre- and posttransplant adolescents in Cali, Colombia.

Jessica M Forero-Delgadillo, Vanessa A Ochoa Jiménez, Alejandro Padilla-Guzmán, María Del Pilar Santamaría-Suarez, María C González-Fernández, Mara Medeiros, Pierina Parraga, María E Díaz-González de Ferris, Mario Miguel Barbosa, Ana María Portilla-Buenaventura and 1 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06836544 (Efficacy of the ALL YOU NEED is LOVE Healthcare Transition Syllabus Among Pre- and Posttransplant Adolescents in Cali, Colombia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06836544 nacompletednot on this map

Efficacy of the ALL YOU NEED is LOVE Healthcare Transition Syllabus Among Pre- and Posttransplant Adolescents in Cali, Colombia

TypeinterventionalSponsorFundacion Clinica Valle del LiliRan2016 to 2017Enrolled35ConditionsRenal TransplantArmsALL YOU NEED IS LOVE syllabus
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jessica M Forero-DelgadilloFacultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.
Vanessa A Ochoa JiménezFacultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.
Alejandro Padilla-GuzmánCentro de Investigaciones Clínicas, Fundación Valle del Lili Cali, Career 98 #18-49, Valle del Cauca, Cali, 760032, Colombia.
María Del Pilar Santamaría-SuarezDepartamento materno infantil, servicio de nefrología pediátrica, Fundación Valle del Lili, Cali, Colombia.
María C González-FernándezDepartamento materno infantil, servicio de nefrología pediátrica, Fundación Valle del Lili, Cali, Colombia.
Mara MedeirosNephrology Research and Diagnosis Unit, Federico Gómez Children's Hospital of México, Mexico City, Mexico.
Pierina ParragaDepartment of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
María E Díaz-González de FerrisDepartment of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
Mario Miguel BarbosaFacultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.
Ana María Portilla-BuenaventuraCentro de Investigaciones Clínicas, Fundación Valle del Lili Cali, Career 98 #18-49, Valle del Cauca, Cali, 760032, Colombia. ana.portilla.bu@fvl.org.co.
Jaime M RestrepoFacultad de Ciencias de la Salud, Universidad Icesi, Cali, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo achieve optimal outcomes, adolescents with chronic or end-stage kidney disease must undergo healthcare transition (HCT) preparation from a pediatric- to an adult-focused setting. The pediatric nephrology group at the Fundación Valle del Líli in Cali, Colombia, collaborated with the University of North Carolina Chapel Hill STAR

methodsWe conducted a pre-test/post-test quasi-experimental study without control group in 11- to 21-year-old consecutive patients with kidney failure followed at the Fundación Valle de Lili. Using the TRxANSITION Index, we measured HCT readiness skills before and after implementing the "ALL YOU NEED IS LOVE" syllabus, an educational curriculum delivered in three monthly 2-hour sessions. Analysis was performed using linear mixed models in R Studio software to evaluate intervention effects while accounting for participant characteristics.

resultsWe enrolled 35 patients (57% female, median age 15.4 years [IQR: 12.6-17.1]). Most patients (77%) had received dialysis pre-transplant and 68% had congenital anomalies of the kidneys and urinary tract. Mothers were primary caregivers for 85% of patients. Linear mixed models showed that post-intervention scores increased significantly across all measures (β = 3.28, 95% CI 2.64-3.92, p < 0.001 for transition scores; β = 1.93, 95% CI 1.48-2.38, p < 0.001 for parent scores; β = 9.31, 95% CI 7.66-10.96, p < 0.001 for total scores). College education was associated with higher baseline scores (β = 2.38, 95% CI 0.42-4.35, p = 0.019 for transition scores; β = 7.58, 95% CI 1.23-13.93, p = 0.021 for total scores). Male participants showed slightly lower initial scores (β = - 0.88, 95% CI - 1.76 to 0.00, p = 0.051).

conclusionIn this cohort of youth with kidney failure from Cali, Colombia, implementation of the Spanish version of the "ALL YOU NEED IS LOVE" syllabus was associated with significant improvements in HCT readiness. Linear mixed models demonstrated robust intervention effects across all domains, with educational level emerging as a significant moderator of intervention effectiveness. Further longitudinal studies are needed to evaluate the long-term impact and sustainability of these improvements in transition readiness scores.

trial registrationThis study was retrospectively registered at ClinicalTrials.gov (NCT06836544, https://clinicaltrials.gov/ct2/show/NCT06836544 ) on February 10, 2025.

Indexed as

CurriculumKidney Failure, ChronicKidney TransplantationPatient Education as TopicTransition to Adult CareAdolescentChildColombiaFemaleHumansMaleYoung AdultAdolescentsChronic kidney diseaseHealthcare transition and patient educationKidney transplantYoung adultYouth

Identifiers

PMID40234817
PMCPMC11998162

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.