Evidence map›Paper›PMID 40234787›Full record

ArticleBMC public health2025

Short-term air pollution exposure and risk of respiratory pathogen infections: an 11-year case-crossover study in Guangzhou, China.

Wenhan Cao, Huimin Huang, Zhenglin Chang, Zhiman Liang, Haiyang Li, Zhangkai Cheng, Baoqing Sun

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenhan CaoDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Huimin HuangDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhenglin ChangDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhiman LiangDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Haiyang LiDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Zhangkai ChengDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. jasontable@gmail.com.
Baoqing SunDepartment of Clinical Laboratory, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. sunbaoqing@vip.163.com.

Funding

Guangdong Zhong Nanshan Foundation ZNSXS-20220083Guangzhou Municipal Health Science and Technology General Guidance Project 20231A011082Nanshan Talent Project 2022111708151837State Key Laboratory of Respiratory Diseases Independent research project SKLRD-Z-202305
6 · The paper itself

Abstract

backgroundLimited epidemiological evidence exists on the relationship between short-term exposure to air pollutants and respiratory pathogen infections. This study investigates the association between short-term air pollution exposure and respiratory pathogen infections in Guangzhou, southern China.

methodsA time-stratified case-crossover study design was applied. Data from 96,927 patients with suspected respiratory pathogen infections between 2013 and 2023 were collected. The daily air pollutant concentration is obtained from the local environmental monitoring station. Logistic regression was used to assess the effect of air pollutant exposure included in the equation on the risk of respiratory pathogen infection. Generalized additive models were used to analyze the relationship between pollutant exposure and hospital visits, adjusting for potential confounders such as temperature and precipitation. Sub-group analysis was performed to estimate the reliability of the correlations among the subgroups.

resultsThe logistic regression model shows that PM

conclusionThis large-scale epidemiological study demonstrates significant associations between short-term air pollutant exposure and respiratory infections, particularly highlighting the risks of NO

Indexed as

Air PollutantsAir PollutionEnvironmental ExposureRespiratory Tract InfectionsAdolescentAdultAgedChildChild, PreschoolChinaCross-Over StudiesFemaleHumansInfantMaleMiddle AgedAir PollutantsNitrogen DioxideParticulate MatterAir pollutionCase-crossover studyRespiratory infectionsShort-term exposureSynergistic pollutant effects

Identifiers

PMID40234787
PMCPMC11998126

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.