ArticleBMC microbiology2025
Molecular epidemiological analysis and research on resistance and virulence of carbapenem-resistant Klebsiella pneumoniae in a tertiary hospital from 2016 to 2023.
Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mortality risk of carbapenem-resistant hypervirulentFrontiers in public health · 2025Pooled it
- Molecular characteristics and analysis of drug resistance-virulence correlation of carbapenem-resistantMicrobiology spectrum · 2026Article
- Molecular Epidemiological Analysis of Carbapenem-Resistant Hypervirulent Klebsiella Pneumoniae in Cangzhou Central Hospital from 2021 to 2024.Pakistan journal of medical sciences · 2026Article
- Genomic and functional characterization of ST11-KL64 hypervirulence-associated carbapenem-resistantFrontiers in microbiology · 2026Article
- Multicenter Surveillance ofInfection and drug resistance · 2026Article
- Mechanistic insights into the formation and spread of carbapenem-resistant hypervirulentMicrobial genomics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCarbapenem-resistant Klebsiella pneumoniae (CRKP) represents a significant global threat due to its high prevalence rates and limited therapeutic options. The primary objective of this study was to investigate the clinical distribution and molecular epidemiology of CRKP collected between 2016 and 2023 from a tertiary care hospital in northern China.
methodsPolymerase chain reaction (PCR) assays were used to identify resistance and virulence genes, while various assessments, including the string test and biofilm formation analysis, assessed CRKP's virulence. Multilocus sequence typing (MLST) and whole-genome sequencing were employed to elucidate strain classification and plasmid characteristics.
resultsThe study identified 100 unique CRKP strains, primarily isolated from neurosurgery and ICU, with sputum as the most common specimen type. The majority of strains harbored bla
conclusionThe emergence of high resistance and hypervirulence in CRKP requires vigilance, enhanced surveillance, and stringent infection control measures to limit its spread.
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