Evidence map›Paper›PMID 40234701›Full record

ArticleScientific reports2025

Assessing ChatGPT 4.0's Capabilities in the United Kingdom Medical Licensing Examination (UKMLA): A Robust Categorical Analysis.

Octavi Casals-Farre, Ravanth Baskaran, Aditya Singh, Harmeena Kaur, Tazim Ul Hoque, Andreia de Almeida, Marcus Coffey, Athanasios Hassoulas

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Answer to the letter to the editor of X. Zhang, et al. concerning "AI versus the spinal surgeons in the management of controversial spinal surgery scenarios" by Mehmet, S. et al. (Eur spine J [2025]: doi.org/10.1007/s00586-025-08825-w).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  9. Article
  10. Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerations.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Octavi Casals-Farre *Centre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom.
Ravanth Baskaran *Centre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom.
Aditya Singh *Centre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom.
Harmeena KaurUniversity of Southampton School of Medicine, 12 University Rd, Southampton, SO17 1BJ, United Kingdom.
Tazim Ul HoqueKeele University School of Medicine, Keele University, University Road, Staffordshire, ST5 5BG, United Kingdom.
Andreia de AlmeidaCentre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom.
Marcus CoffeyCentre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom.
Athanasios HassoulasCentre for Medical Education (C4ME), School of Medicine, Cardiff University, Heath Park Campus, Cardiff, CF14 4YS, United Kingdom. hassoulasa2@cardiff.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in the various applications of artificial intelligence will have important implications for medical training and practice. The advances in ChatGPT-4 alongside the introduction of the medical licensing assessment (MLA) provide an opportunity to compare GPT-4's medical competence against the expected level of a United Kingdom junior doctor and discuss its potential in clinical practice. Using 191 freely available questions in MLA style, we assessed GPT-4's accuracy with and without offering multiple-choice options. We compared single and multi-step questions, which targeted different points in the clinical process, from diagnosis to management. A chi-squared test was used to assess statistical significance. GPT-4 scored 86.3% and 89.6% in papers one-and-two respectively. Without the multiple-choice options, GPT's performance was 61.5% and 74.7% in papers one-and-two respectively. There was no significant difference between single and multistep questions, but GPT-4 answered 'management' questions significantly worse than 'diagnosis' questions with no multiple-choice options (p = 0.015). GPT-4's accuracy across categories and question structures suggest that LLMs are competently able to process clinical scenarios but remain incapable of understanding these clinical scenarios. Large-Language-Models incorporated into practice alongside a trained practitioner may balance risk and benefit as the necessary robust testing on evolving tools is conducted.

Indexed as

Clinical CompetenceEducational MeasurementLicensure, MedicalGenerative Artificial IntelligenceHumansUnited KingdomChatGPTExamFinalsMedical student

Identifiers

PMID40234701
PMCPMC12000555

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.