Evidence map›Paper›PMID 40234563›Full record

ArticleScientific reports2025

Dogs' olfactory resting-state functional connectivity is modulated by age and brain shape.

Asami Nakaimuki, Bernadett Paska, Laura V Cuaya, Raúl Hernández-Pérez, Kalman Czeibert, Dóra Szabó, Eniko Kubinyi, Attila Andics

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work.Animals : an open access journal from MDPI · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asami NakaimukiDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary. av3acsca0amrioi@gmail.com.
Bernadett PaskaDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Laura V CuayaDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Raúl Hernández-PérezDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Kalman CzeibertDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Dóra SzabóDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Eniko KubinyiDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Attila AndicsDepartment of Ethology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans have long applied canine olfaction in various contexts. Dog olfactory brain networks have recently been mapped by anatomical measures, but functional connections remain unexplored. Also, whereas individual characteristics, including age, sex, and brain shape, are known to affect olfactory performance, their covariation with olfactory functional networks is unknown. To address these, we investigated dogs' resting-state functional connectivities between anatomically defined olfactory regions and assessed whether and how their olfactory functional network is affected by age, sex, and brain shape. Olfactory functional connectivity strength exhibited negative correlations with both age and brain shape: older dogs and those with rounder-shaped brains demonstrated lower functional connectivity, respectively, but no effect of sex was found. The results suggest that both aging and brain morphology can negatively impact a dog's sense of smell, and older dogs and dogs with rounder-shaped brains may have diminished olfactory performance.

Indexed as

AgingBrainOlfactory PathwaysSmellAge FactorsAnimalsBrain MappingDogsFemaleMagnetic Resonance ImagingMaleRestDogFunctional connectivityIndividual differencesOlfactionResting-state fMRI

Identifiers

PMID40234563
PMCPMC12000304

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.