Evidence map›Paper›PMID 40234524›Full record

ArticleScientific reports2025

Enhanced individual difference of functional brain network induced by volitional eyes closing.

Yi Zhang, Guiyang Lv, Panpan Han, Nianqiang Peng, Longhui Li, Jun Gu, Yue Liu, Xin Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yi ZhangDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, 315201, China.
Guiyang LvInstitute of Big Data and Artificial Intelligence in Medicine, School of Electronics and Information Engineering, Taizhou University, Taizhou, 318000, China.
Panpan HanDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, 315201, China.
Nianqiang PengTin Ka Ping Moral Education Research Center, Zhejiang Normal University, Jinhua, 321004, China.
Longhui LiDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, 315201, China.
Jun GuDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, 315201, China.
Yue LiuDepartment of Psychiatry, Affiliated Kangning Hospital of Ningbo University, Ningbo, 315201, China.
Xin ShiDepartment of Neurosurgery, Shenzhen University General Hospital, Shenzhen, 518000, China. shixin6605@126.com.

Funding

Health and Medical Science and Technology Plan Project in Ningbo City No. 2024Y19
6 · The paper itself

Abstract

Volitional eyes closing (EC) can promote the interoceptive thoughts that vary considerably among individuals. Although this behavior is known to recruit a large-scale brain network as its neural underpinning, individual variability in such network recruitment remains unexplored. Here, we compared the intersubject variability in functional connectivity (IVFC) between the EC and eyes opening conditions. It was found that the IVFC significantly increased during the EC condition, which could be replicated in different public datasets and multi-resolution parcellations. Moreover, the EC-enhanced IVFC focused on selective subsets of FCs, with predominant impact on the default-mode, dorsal attention, and visual networks. Finally, a positive relationship was discovered between EC-enhanced IVFC and deep involvement in the task-unrelated thoughts that was measured with an additional dataset. Collectively, these results suggested that enhanced individual difference characterize the functional network of volitional EC, with widespread impact on cognitive systems and potential connection to task-unrelated thoughts.

Indexed as

BrainIndividualityNerve NetVolitionAdultAttentionBrain MappingFemaleHumansMagnetic Resonance ImagingMaleYoung AdultFunctional brain networkIndividual differenceTask-unrelated thoughtsVolitional eyes closing

Identifiers

PMID40234524
PMCPMC12000520

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.