Evidence map›Paper›PMID 40234438›Full record

ArticleScientific data2025

Comprehensive Whole Genome Sequencing Dataset of Mycobacterium tuberculosis Strains Collected Across Italy.

Arash Ghodousi, Angela Cannas, Elisa Tagliani, Virginia Batignani, Francesco Bisognin, Emanuele Borroni, Ornella Butera, Luigi Ruffo Codecasa, Paola Dal Monte, Flavio De Maio and 13 more

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. What is new in tuberculosis?Clinical medicine (London, England) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Arash GhodousiVita-Salute San Raffaele University, Milan, Italy.ORCID http://orcid.org/0000-0001-9334-1573
Angela CannasNational Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.
Elisa TaglianiDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Virginia BatignaniDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesco BisogninMicrobiology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138, Bologna, Italy.
Emanuele BorroniDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ornella ButeraNational Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.
Luigi Ruffo CodecasaRegional TB Reference Centre and Laboratory, Villa Marelli Institute/Niguarda Hospital, Milano, Italy.
Paola Dal MonteMicrobiology Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138, Bologna, Italy.
Flavio De MaioDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie - Sezione di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Giovanni DeloguDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie - Sezione di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID http://orcid.org/0000-0003-0182-8267
Giovanna MatteiGeneral Directorate for personal care, health and welfare, Emilia Romagna Region, Bologna, Italy.
Giulio MatteoGeneral Directorate for personal care, health and welfare, Emilia Romagna Region, Bologna, Italy.
Francesco MessinaNational Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.ORCID http://orcid.org/0000-0001-8076-7217
Maryam OmraniDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Cinzia PerilliGeneral Directorate for personal care, health and welfare, Emilia Romagna Region, Bologna, Italy.
Michela SaliDipartimento di Scienze biotecnologiche di base, cliniche intensivologiche e perioperatorie - Sezione di Microbiologia, Università Cattolica del Sacro Cuore, Rome, Italy.
Giovanni SotgiuDipartimento di Medicina Clinica e Sperimentale, Università degli Studi dui Sassari, Sassari, Italy.
Marina TadoliniDepartment of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, 40138, Bologna, Italy.
Stefania TorriRegional TB Reference Centre and Laboratory, Villa Marelli Institute/Niguarda Hospital, Milano, Italy.
Chiara VismaraMicrobiological Analysis Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Enrico GirardiNational Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.
Daniela Maria CirilloDivision of Immunology, Transplantation, and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy. cirillo.daniela@hsr.it.ORCID http://orcid.org/0000-0001-6415-1535

Funding

Ministero della Salute (Ministry of Health, Italy) Ricerca Corrente Line n. 4, Project n. 1
6 · The paper itself

Abstract

Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex (MTBC), remains a major global health challenge. Whole genome sequencing (WGS) offers an invaluable tool for understanding the genetic diversity and drug resistance profiles of MTBC. This study provides a comprehensive WGS dataset of 2,520 MTBC isolates collected from four Italian regions-Lombardy, Piedmont, Emilia-Romagna, and Lazio-between 2017 and 2020. The dataset includes genomic data along with associated metadata, such as geographic location and drug susceptibility profiles, providing a robust resource for studying TB epidemiology and transmission dynamics. This collection represents the largest publicly available MTBC WGS dataset from Italy and has been validated to ensure accuracy and completeness. By making this dataset accessible, we aim to support collaborative research, facilitate the exploration of MTBC evolution and drug resistance, and enhance TB surveillance efforts.

Indexed as

Genome, BacterialMycobacterium tuberculosisTuberculosisWhole Genome SequencingHumansItaly

Identifiers

PMID40234438
PMCPMC12000572

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.