ArticleNature communications2025
Dose-response relationship between evening exercise and sleep.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Dose-response relationship between physical activity and subjective sleep quality in patients with insomnia: a systematic review and Bayesian meta-analysis of randomized controlled trials.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- The effectiveness of dance interventions on sleep quality: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Mapping the effects of exercise on cognition and physical function: a scoping review of rodent studies.Frontiers in physiology · 2026Pooled it
- Effects of exercise interventions on sleep quality in adolescents: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- The effect of evening swimming exercise on sleep parameters in male swimmers.Physiological reports · 2026Article
- Body and Mind Intertwined: Physical Activity Intensity, Sleep Quality, and Depressive Symptoms: Cross-Sectional Associations and Exploratory Path Analysis.Journal of clinical medicine · 2026Article
- Sleep-Wake Dysregulation in Human African Trypanosomiasis: From Neuroinvasion to Neuronal Dysfunction.Clocks & sleep · 2026Review
- Article
- Sleep Quality and Its Sociodemographic, Behavioural, Clinical, and Regional Correlates Among Adults in Kazakhstan: A National Cross-Sectional Survey.Clocks & sleep · 2026Article
- Strengthening recovery, enduring sleep. An ecologically valid assessment of sleep quantity and quality in hybrid athletes: does training mode matter?European journal of applied physiology · 2026Article
- Optimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff.Sports medicine (Auckland, N.Z.) · 2026Review
- Exercise Timing in Sport: Molecular and Physiological Mechanisms Linking Performance, Recovery, and Biological Cost.International journal of molecular sciences · 2026Review
- Real-world effects of alcohol on heart rate, sleep, and physical activity by age and sex.PLOS digital health · 2026Article
- Associations of sedentary behaviour and physical activity with stress-related sleep disturbance among adolescents in 69 countries: a population-based study.Journal of global health · 2026Article
- The association between activity patterns and malignant neoplasms of female genital organs: a prospective cohort study of UK biobank.Frontiers in endocrinology · 2026Article
- Self-rated health is associated with sleep quality in teacher education students.Frontiers in public health · 2026Article
- Exercise timing as a potential temporal regulator of neurolymphatic physiology in neurodegenerative proteinopathies: a mechanistic framework.Frontiers in neuroscience · 2026Review
- Physical exercise as a modulator of the sleep-obesity interaction: metabolic, neuroendocrine and circadian mechanisms.Frontiers in sleep · 2026Review
- Repeated device-based measures of daily movement, sedentary behavior, and sleep at 6 months postpartum: the Pregnancy Environment and Lifestyle Study-2 cohort.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Bidirectional effects of physical activity and sleep on health: evidence and future directions.Frontiers in sports and active living · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Public health guidelines recommend exercise as a key lifestyle intervention for promoting and maintaining healthy sleep function and reducing disease risk. However, strenuous evening exercise may disrupt sleep due to heightened sympathetic arousal. This study examines the association between strenuous evening exercise and objective sleep, using data from 14,689 physically active individuals who wore a biometric device during a one-year study interval (4,084,354 person-nights). Here we show later exercise timing and higher exercise strain are associated with delayed sleep onset, shorter sleep duration, lower sleep quality, higher nocturnal resting heart rate, and lower nocturnal heart rate variability. Regardless of strain, exercise bouts ending ≥4 hours before sleep onset are not associated with changes in sleep. Our results suggest evening exercise-particularly involving high exercise strain-may disrupt subsequent sleep and nocturnal autonomic function. Individuals aiming to improve sleep health may benefit from concluding exercise at least 4 hours before sleep onset or electing lighter strain exercises within this window.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.