ArticleActa neurologica Belgica2025
Clinical characteristics and treatment of patients hospitalized with status migrainosus: a retrospective analysis.
Article in Acta neurologica Belgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundsStatus Migrainosus is not rare, but there is still very little research data on this aspect, and treatment and diagnosis face huge challenges. OBJECTS: The purpose of this study was to characterize the clinical characteristics and current treatment status of status migrainosus patients hospitalized in the Department of Neurology.
methodsThis retrospective study examined patients with status migrainosus who were hospitalized in the Department of Neurology at a tertiary hospital in Chengdu, China, from August 1, 2015, to July 31, 2024. This study analyzed the demographic characteristics, clinical features, and treatment approaches of these status migrainosus patients.
resultsAmong the 1,237 patients hospitalized with a primary complaint of headache, 26 were ultimately diagnosed with status migrainosus. Of these status migrainosus patients, 21 patients with complete information were analyzed. The cohort predominantly consisted of middle-aged women, with most reporting moderate to severe headache intensity. The most common triggers identified were lack of sleep (66.7%) and mood disorders (42.8%). The average duration of status migrainosus was 9.3 days. In terms of treatment, NSAIDs were the most frequently administered (95.2%). During hospitalization, the most commonly used oral analgesics were NSAIDs and triptans, while intravenous treatments primarily included dexamethasone and valproic acid. 87.5% (14 out of 16) of the patients received preventive migraine treatment following discharge.
conclusionThe clinical characteristics of Status Migrainosus are generally similar to those of episodic migraine. Treatment to terminate the headache attack often requires the combined use of multiple drugs.
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