Evidence map›Paper›PMID 40233931›Full record

ArticleVirulence2025

Mannan is a context-dependent shield that modifies virulence in

Gabriela Fior Ribeiro, Emily L Priest, Helen Heaney, Jonathan P Richardson, Delma S Childers

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Journal of medical microbiology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriela Fior RibeiroInstitute of Medical Sciences, Aberdeen Fungal Group, University of Aberdeen, Aberdeen, UK.ORCID 0000-0003-3611-8249
Emily L PriestCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.ORCID 0000-0002-4307-7177
Helen HeaneyInstitute of Medical Sciences, Aberdeen Fungal Group, University of Aberdeen, Aberdeen, UK.
Jonathan P RichardsonCentre for Host-Microbiome Interactions, Faculty of Dentistry, Oral and Craniofacial Sciences, King's College London, London, UK.ORCID 0000-0001-9638-2725
Delma S ChildersInstitute of Medical Sciences, Aberdeen Fungal Group, University of Aberdeen, Aberdeen, UK.ORCID 0000-0003-2869-7332

Funding

Medical Research Council
6 · The paper itself

Abstract

Fungal-host interaction outcomes are influenced by how the host recognizes fungal cell wall components. Mannan is a major cell wall carbohydrate and can be a glycoshield that blocks the inner cell wall β-1,3-glucan from activating pro-inflammatory immune responses. Disturbing this glycoshield in

Indexed as

MannansSaccharomycetalesAnimalsbeta-GlucansCell WallFungal ProteinsHost-Pathogen InteractionsLarvaMacrophagesMiceMothsVirulencebeta-GlucansFungal ProteinsMannansCandida glabratacell wallGalleria mellonellaMNN10pathogenesis

Identifiers

PMID40233931
PMCPMC12001547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.