Evidence map›Paper›PMID 40233815›Full record

ArticleEndoscopy2025

Endoscopic direct diverticulitis therapy for acute uncomplicated diverticulitis.

Jian-Zhen Ren, Jun Cai, Bo Li, Guang Yang, Su-Huan Liao, Jia-Kuan Chen, Yi-Tian Guo, Yang-Bor Lu, Si-Lin Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian-Zhen RenDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Jun CaiDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Bo LiDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Guang YangDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Su-Huan LiaoDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Jia-Kuan ChenDepartment of Radiology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Yi-Tian GuoDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Yang-Bor LuDepartment of Digestive Disease, Xiamen Chang Gung Hospital, Hua Qiao University, Xiamen, China.
Si-Lin HuangDepartment of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.

Funding

The Clinical Teaching Base Teaching Reform Research Project of School of Medicine in Shenzhen University YXBJG202426
6 · The paper itself

Abstract

Background: The global prevalence of acute uncomplicated diverticulitis is increasing, and patient care for this condition is experiencing a paradigm shift. This study evaluated the diagnostic and therapeutic value of endoscopic direct diverticulitis therapy (EDDT) using cholangioscope-assisted colonoscopy for acute uncomplicated diverticulitis. Methods: Patients with computed tomography-confirmed acute uncomplicated diverticulitis (Hinchey stage Ia or Ib) who underwent EDDT between July 2023 and December 2024 were included. The technical success rate of EDDT, procedure time, endoscopic findings, symptom resolution, and recurrence were documented. Results: 12 patients (mean age 45.2 [SD 10.1] years, 10 males) underwent EDDT. Technical success was achieved in all 12 patients (100%). Cholangioscope-assisted colonoscopy revealed fecaliths with pus in seven patients, copious purulent collection in four, edematous inflammatory mucosa in five, and bleeding in one. Corresponding treatments were applied without complications. Abdominal pain resolved immediately after EDDT, and inflammatory parameters returned to normal. No recurrences were reported over a mean follow-up of 4 months (range 1–10 months). Conclusions: EDDT utilizing cholangioscope-assisted colonoscopy was a feasible alternative treatment for acute uncomplicated diverticulitis, offering diagnostic and therapeutic advantages through direct visualization. Although preliminary results are promising, further studies with larger cohorts are warranted to confirm its efficacy and long-term outcomes.

Indexed as

ColonoscopyDiverticulitis, ColonicAbdominal PainAcute DiseaseAdultAgedFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesTreatment Outcome

Identifiers

PMID40233815
PMCPMC12507040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.