Evidence map›Paper›PMID 40232722›Full record

ArticleJAMA network open2025

Rurality and Area Deprivation and Outcomes After Out-of-Hospital Cardiac Arrest.

Lakota Cheek, Robert H Schmicker, Remle Crowe, Emily Goren, Amanda West, Jason McMullan, Colin Raelson, Jeanne Poole, Karen Adams, Antje Hoering and 2 more

Abstract read
In one paragraph

Article in JAMA network open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lakota CheekDepartment of Emergency Medicine, University of Washington, Seattle.
Robert H SchmickerDepartment of Biostatistics, University of Washington, Seattle.
Remle CroweESO Inc, Austin, Texas.
Emily GorenCancer Research and Biostatistics, Seattle, Washington.
Amanda WestDepartment of Emergency Medicine, University of Washington, Seattle.
Jason McMullanDepartment of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio.
Colin RaelsonSwedish Heart and Vascular Institute, Swedish Cherry Hill Campus, Seattle, Washington.
Jeanne PooleDepartment of Medicine, University of Washington, Seattle.
Karen AdamsUniversity of Washington-Harborview Center for Prehospital Emergency Care, Seattle.
Antje HoeringCancer Research and Biostatistics, Seattle, Washington.
Brent MyersESO Inc, Austin, Texas.
Graham NicholUniversity of Washington-Harborview Center for Prehospital Emergency Care, Seattle.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Importance: Large regional variations in outcomes after out-of-hospital cardiac arrest (OHCA) exist. Objective: To assess whether neighborhood rurality or economic deprivation where an OHCA occurred is associated with variation in emergency medical services (EMS) outcomes after OHCA. Design, Setting, and Participants: This cohort study used data collated by ESO Inc on US adult patients (aged ≥18 years) with nontraumatic OHCA receiving chest compressions or defibrillation from EMS between January 1, 2022, and December 31, 2023. Exposures: Rurality was assessed using Rural-Urban Commuting Area codes. Deprivation was assessed using the Area Deprivation Index. Both were derived from US Census data and grouped by EMS agency. Main Outcomes and Measures: Outcomes were restoration of spontaneous circulation (ROSC) at emergency department (ED) arrival, survival to hospital discharge, and favorable discharge destination. Discharge outcomes were only available for patients transported to hospitals using health data exchange. Generalized estimating equations were used to account for correlated data. Results: A total of 162 289 patients with OHCA had resuscitation attempted (median [IQR] age, 66 [53-76] years; 62.3% male). Overall, 28.1% of these patients lived in rural or suburban locations, 12.3% lived in areas with high deprivation, 18.7% had a first rhythm of ventricular tachycardia or ventricular fibrillation or shockable by automated external defibrillator rhythm, and 27.6% received bystander cardiopulmonary resuscitation. The mean (SD) EMS response time was 8.7 (5.6) minutes. Upon arrival at the ED, 23.7% of patients had ROSC. Compared with OHCAs in urban areas with low deprivation, those in rural areas with high deprivation (adjusted odds ratio [AOR], 0.81; 95% CI, 0.72-0.91), moderate deprivation (AOR, 0.75; 95% CI, 0.70-0.81), or low deprivation (AOR, 0.74; 95% CI, 0.62-0.88) had lower odds of ROSC at ED arrival. Among patients transported to hospitals using health data exchange, OHCAs in urban areas with high or moderate deprivation had lower odds of survival (AOR, 0.78 [95% CI, 0.68-0.90] and 0.82 [95% CI, 0.75-0.89], respectively) and favorable discharge destination (AOR, 0.65 [95% CI, 0.53-0.79] and 0.77 [95% CI, 0.69-0.87], respectively). Conclusions and Relevance: In this cohort study, OHCAs in rural areas of all levels of economic deprivation were associated with less ROSC at ED arrival vs urban areas with low deprivation, and OHCAs in urban areas with high or moderate deprivation are associated with less survival and less favorable discharge destination, suggesting worse neurologic outcomes. Care improvements alone may not reduce geographic differences in outcomes after OHCA.

Indexed as

Cardiopulmonary ResuscitationEmergency Medical ServicesOut-of-Hospital Cardiac ArrestRural PopulationAgedCohort StudiesFemaleHumansMaleMiddle AgedUnited States

Identifiers

PMID40232722
PMCPMC12000968

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.