Trial reportLasers in medical science2025
The efficacy of high-intensity laser and short-wave diathermy both combined with exercises in patients with knee osteoarthritis: a randomized comparative study.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The importance of power in photobiomodulation: a systematic review and meta-analysis of high-intensity laser therapy.Frontiers in integrative neuroscience · 2026Pooled it
- Local hyperthermia therapy for the pain management of knee osteoarthritis: a network meta-analysis of randomized controlled trials.EFORT open reviews · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study aimed to investigate the effects of high-intensity laser therapy and short-wave diathermy, both with exercise, on pain, physical function, and quality of life in patients with knee osteoarthritis and compare the efficacy of these modalities. This head-to-head randomized study included sixty patients diagnosed with primary knee osteoarthritis (OA) according to the American College of Rheumatology (ACR) criteria and radiologically evaluated as Kellgren-Lawrence stages 2 and 3 bilateral OA patients were divided into two groups according to the therapy: high-intensity laser (HILT) with exercise (n = 30) and short-wave diathermy (SWD) with exercise (n = 30) in which patients treated for 2 weeks (5 days a week for a total of 10 sessions). Visual Analogue Scale (VAS), The Western Ontario and McMaster Universities Arthritis Index (WOMAC), Timed Up and Go, Stair Climb, 30-s chair-stand, 40-meter Fast-paced Walk, and Short Form Survey (SF-36) tests were performed before and after treatments. Compared to pretreatment, HILT + exercise therapy improved all the test results, while SWD + exercise therapy also improved test scores except for the 30-s chair-stand and 40-meter Fast-paced Walk tests. When HILT + exercise therapy was compared with SWD + exercise therapy, HILT treatment was more effective in all tests except the Stair Climb and 40-meter Fast-paced Walk tests. Although the treatments applied with exercise were effective in both groups, HILT was more effective than SWD in terms of pain, physical, functional, and quality of life. HILT was recommended in the treatment plan of patients with stage 2-3 knee osteoarthritis.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.