Evidence map›Paper›PMID 40232596›Full record

ReviewProbiotics and antimicrobial proteins2025

Exploring Innovative Approaches for Managing Spinal Cord Injury: A Comprehensive Review of Promising Probiotics and Postbiotics.

Fereshteh Jamali, Safa Mousavi, Aziz Homayouni-Rad, Ali Meshkini, Hossein Alikhah, Jalil Houshyar, Saba Kamalledin Moghadam, Seyyed Mohammad Yaghoubi, Kimia Motlagh Asghari, Masoud Torbati Ilkhchi and 1 more

Abstract readReview
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In one paragraph

Review in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fereshteh JamaliNeurosurgery Department, Children'S Hospital at Montefiore, New York City, USA.
Safa MousaviDepartment of Public Health, College of Health and Human Services, California State University, Fresno, CA, USA.
Aziz Homayouni-RadDepartment of Food Science and Technology, Faculty of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.
Ali MeshkiniNeuroscience Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hossein AlikhahMaragheh University of Medical Sciences, Maragheh, Iran.ORCID 0000-0002-2224-4319
Jalil HoushyarEndocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Saba Kamalledin MoghadamDepartment of Food Science and Technology, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. sabakamalledinm@sbmu.ac.ir.ORCID 0000-0003-4858-5469
Seyyed Mohammad YaghoubiImmunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Kimia Motlagh AsghariPhysical Medicine and Rehabilitation Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Masoud Torbati IlkhchiShohada Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Seyed Ahmad Naseri AlaviDepartment of Neurosurgery, School of Medicine, Emory University, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord injury (SCI) affects millions of people worldwide annually, presenting significant challenges in functional recovery despite therapeutic advancements. Current treatment strategies predominantly focus on stabilizing the spinal cord and facilitating neural repair, yet their effectiveness remains uncertain and controversial. Recent scientific investigations have explored the potential of probiotics and postbiotics to modulate inflammation, influence neurotransmitters, and aid in tissue repair, marking a potential paradigm shift in SCI management. This review critically evaluates these innovative approaches, emphasizing their ability to harness the natural properties of microorganisms within the body to potentially enhance outcomes in SCI treatment. By analyzing the latest research findings, this review provides valuable insights into how probiotics and postbiotics can revolutionize inflammation management and neurological recovery following SCI, underscoring their promising role in future therapeutic strategies aimed at improving the quality of life of SCI patients globally.

Indexed as

ProbioticsSpinal Cord InjuriesAnimalsHumansQuality of LifeGut–brain axisNeuroinflammationPostbioticsProbioticsSpinal cord injury (SCI)

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.